HIGH GRADE GLIOMAS
Clinical trials for HIGH GRADE GLIOMAS explained in plain language.
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Two-Pronged gene therapy takes on deadly brain tumors
Disease control Recruiting nowThis trial tests a new gene therapy called TGX-007 for people with a fast-growing brain cancer called glioblastoma. The therapy uses a harmless virus to deliver two special instructions: one helps a common drug kill cancer cells, and the other wakes up the immune system to attack…
Matched conditions: HIGH GRADE GLIOMAS
Phase: PHASE1, PHASE2 • Sponsor: Trogenix ltd • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Promising combo targets Hard-to-Treat childhood cancers
Disease control Recruiting nowThis study is testing a combination of two drugs—a targeted radioactive drug (177Lu-DOTATATE) and a PARP inhibitor (olaparib)—in children and teens aged 3 to 18 with certain solid tumors that have come back or not responded to treatment. The goal is to see if the combination is s…
Matched conditions: HIGH GRADE GLIOMAS
Phase: PHASE1, PHASE2 • Sponsor: Fundación de investigación HM • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New hope for kids with tough brain tumors: gene therapy meets immunotherapy and radiation
Disease control Recruiting nowThis early-phase trial is testing a combination of three treatments for children whose brain tumors have come back or not responded to standard care. The experimental drug SGT-53 delivers a normal TP53 gene to tumor cells, and is given alongside the immunotherapy Nivolumab and ra…
Matched conditions: HIGH GRADE GLIOMAS
Phase: EARLY_PHASE1 • Sponsor: Children's National Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Supercharged immune cells take on deadly brain tumors
Disease control Recruiting nowThis early-phase trial tests a new treatment for people with recurrent glioblastoma, a fast-growing brain cancer. The treatment uses a patient's own immune cells (NK cells) that have been engineered in a lab to better recognize and attack tumor cells. The cells are delivered dire…
Matched conditions: HIGH GRADE GLIOMAS
Phase: PHASE1 • Sponsor: Beijing Biotech • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Glow-in-the-Dark drug could help surgeons spot brain cancer
Knowledge-focused Recruiting nowThis early-phase trial tests a special version of the immunotherapy drug nivolumab that has a fluorescent dye attached (nivo800). The dye makes the drug glow under near-infrared light, allowing researchers to see exactly where the drug goes in the tumor during surgery. About 38 a…
Matched conditions: HIGH GRADE GLIOMAS
Phase: EARLY_PHASE1 • Sponsor: Eben Rosenthal • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC