Gastric bypass secrets: intestine rewires metabolism
NCT ID NCT02710370
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how gastric bypass surgery changes the way the small intestine processes sugar and other fuels, which may explain why the surgery improves obesity and type 2 diabetes. Researchers will collect intestinal tissue and blood samples from 32 people before and up to one year after surgery. They will analyze the cells, genes, and metabolites to understand these metabolic changes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could reveal how the intestine drives metabolic improvements after gastric bypass, potentially pointing to new treatments for obesity and type 2 diabetes.
What could go wrong
This is an observational study with only 46 participants, so findings may not apply to everyone. It looks at biological changes, not a new treatment, so direct benefits are not guaranteed.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, 15213, United States