Yale University
Clinical trials sponsored by Yale University, explained in plain language.
-
Peer support may boost HIV treatment success in people who inject drugs
Disease control TerminatedThis study tests whether adding peer-based counseling to standard HIV and opioid treatment helps people who inject drugs stay on their medications and achieve viral suppression. Participants receive either enhanced usual care or extra support from a peer counselor. The goal is to…
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
-
New combo tackles brain tumors in melanoma and kidney cancer patients
Disease control TerminatedThis study tested a combination of two drugs, pembrolizumab and lenvatinib, in 18 adults with melanoma or kidney cancer that had spread to the brain. Participants had already received anti-PD-1/PD-L1 therapy. The goal was to see if the drug combo could shrink or eliminate brain t…
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
-
Heart drug digoxin tested for alcoholic hepatitis – early trial halted
Disease control TerminatedThis small, early-phase study tested whether the heart medication digoxin could reduce inflammation in people with severe alcohol-associated hepatitis. 23 participants were randomly assigned to receive intravenous digoxin or no digoxin for up to 28 days. The trial was terminated …
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
-
New bedwetting alarm tested against standard device – but trial cut short
Symptom relief TerminatedThis study compared a new bedwetting alarm called GoGoband, which wakes a child before they wet the bed, to a standard alarm that sounds after wetting. The trial included 16 children aged 6 to 21 with bedwetting but no ADHD. However, the study was terminated early, so the results…
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
-
Brain zapping study reveals Memory's role in speech learning
Knowledge-focused TerminatedThis study looked at how memory for speech sounds and movements helps people learn to speak. Researchers used a gentle magnetic pulse to temporarily quiet a part of the brain linked to memory, then tested how well healthy adults could adjust their speech. The goal was to understa…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
-
Simple Pre-Surgery test may spot hidden heart damage
Knowledge-focused TerminatedThis study tested whether a brief, low-intensity exercise test before noncardiac surgery could help doctors detect heart injury after surgery better than standard care. Ten adults aged 45 or older participated. Researchers measured heart injury using a blood test for up to three …
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
-
Face stretch study explores link between touch and speech
Knowledge-focused TerminatedThis study looked at whether repeatedly pairing facial skin stretches with speech sounds can change how people perceive speech. Researchers tested 160 right-handed adults with no known neurological issues. The study was terminated early, so results are limited.
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
-
Yale study tests if a pep talk boosts depression drug – but only one person joined
Knowledge-focused TerminatedThis study aimed to see if giving patients extra encouragement before and after esketamine treatment could improve their depression symptoms. Researchers planned to compare a group that received a positive presentation and follow-up session with a group that did not. However, the…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
-
Brain zap study probes how we remember new speech movements
Knowledge-focused TerminatedThis study looked at how certain brain areas help us remember new ways of speaking. Researchers used a gentle brain stimulation technique to temporarily quiet parts of the brain involved in touch and hearing, right after people practiced altered speech sounds. The goal was to see…
Phase: NA • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC