University Of Virginia

This study looked at how well an artificial pancreas system works for teenagers with Type 1 Diabetes over two years. It included 42 kids aged 11 to 13 who were in early puberty. The goal was to see if the system helps keep blood sugar levels stable as their bodies change.

This study tested whether topiramate, a seizure medication, helps people who are dependent on both alcohol and nicotine. 236 adults took either a high or low dose of topiramate or a placebo for 18 weeks. The main goals were to see if the drug helped them stop smoking and reduce h…

This pilot study tested whether using an automated insulin delivery (AID) system for just 10 days can help people with type 2 diabetes safely adjust their long-acting insulin doses. 23 adults who already used insulin injections took part. The goal was to see if the device was saf…

This study tested a continuous glucose monitor (CGM)-based advisory system to help adults with type 1 diabetes better manage their blood sugar. The system gives personalized advice based on glucose readings and the person's behavior and mindset. The goal was to improve glucose co…

This study tested two different medicines to stop bleeding after heart surgery in children aged 2 years or younger. One medicine is a purified protein called fibrinogen concentrate, and the other is a blood product called cryoprecipitate. The goal was to see if the protein works …

This study tested a program called iSIPsmarter to help adults in rural Appalachia drink fewer sugary beverages like soda and sweet tea. About 249 adults who regularly drank sugary drinks were split into two groups: one used the iSIPsmarter program, and the other used a standard h…

This small study tested a new tool called InsuLearn that helps people with type 1 diabetes calculate their insulin doses without needing to count carbohydrates. Seven adults on multiple daily injections used the tool for a day and were compared to their usual care. The goal was t…

This pilot study tested whether a continuous glucose monitor (CGM) can help people with type 2 diabetes adjust their long-acting insulin more effectively than traditional fingerstick checks. Thirty adults already using basal insulin were followed for 18 weeks. The goal was to see…

This study tested a program called UP2UTobacco to help 9th graders stop using tobacco and e-cigarettes. About 600 students took part in group discussions and text messaging to support quitting. Researchers compared those who got the program to those who didn't, checking if more s…

This study tested whether a smartphone app can accurately measure how well your eyes and balance system work together (the vestibulo-ocular reflex). 35 adults with and without balance disorders used the app and a standard computer system. The goal was to see if the app could be a…

This study tested short, easy-to-use digital tools (called micro-interventions) designed to reduce distress and improve well-being in breast cancer survivors. 120 women who had been diagnosed with early-stage breast cancer in the past 5 years and had mild-to-moderate anxiety or d…

This study tested whether a mobile app called IntelliCare can help reduce depression and anxiety in 313 breast cancer survivors diagnosed within the past 5 years. Some participants also received coaching to boost app use. The goal was to see if the app and coaching improve emotio…

This study looked at whether donepezil (Aricept), a drug that boosts a brain chemical called acetylcholine, can help improve walking and balance in people with Parkinson's disease. Six participants took the drug for 12 weeks while researchers measured their walking speed and brai…

This study tested a telephone helpline for people with opioid dependence. Trained counselors provided support, education, and referrals to help manage addiction and pain. The goal was to see if people found the helpline helpful and easy to use.

This study tested whether low-intensity focused ultrasound (LIFU) can safely reduce cravings in people with cocaine use disorder. 25 adults received either real or fake (sham) ultrasound while their brain activity was measured with MRI. The goal was to see if LIFU lowers craving …

This study used a special MRI technique with inhaled helium to measure how fast air moves through the windpipe. Researchers compared 24 healthy volunteers and people with COPD or constrictive bronchitis. The goal was to gather real data to improve computer models that predict air…

This study tested a new way to measure muscle stiffness by taking pictures of the skin on the back. Five adults, either healthy or with mild neck pain, had their skin gently pulled and stretched while cameras recorded the movement. The goal was to see if this simple imaging metho…

This study looked at whether a hiatal hernia (a stomach condition) might be linked to early, unnoticed lung scarring. Researchers compared 14 adults with and without hiatal hernia, measuring stomach fluid in the lungs and blood markers of lung injury. The goal was to find hidden …

This study tested how a pill called 2DG, which is similar to sugar but can't be used for energy, is processed by the body in 9 adults with epilepsy. The idea is that 2DG might stop seizures by blocking the brain's fuel supply during a seizure. Researchers measured drug levels in …

This pilot study tested whether computer models could predict sepsis and necrotizing enterocolitis (NEC) in very low birth weight infants (under 1500 grams). Researchers used existing NICU data to build and test these models. The goal was to see if this approach is feasible, not …

This study looked at how different exercise intensities change levels of ghrelin, a hormone that controls hunger, in 40 adults with obesity or prediabetes. Researchers measured ghrelin in the blood, along with appetite, insulin sensitivity, and blood vessel function. The goal was…

This study tested a group-based program to help endometrial cancer survivors adopt healthier habits. The goal was to lower their risk of other health problems like heart disease and diabetes. Twenty-three survivors who had finished cancer treatment took part in online learning an…