University Of Virginia

This study tests a new treatment for people with metastatic breast or prostate cancer that has stopped responding to standard therapies. The treatment uses the patient's own immune cells, which are collected, coated with a special antibody, and then given back through an IV. The …

This study looks at whether adding exercise to a weight loss medication (tirzepatide) helps people lose more weight and improve health markers like blood sugar and cholesterol. It will involve 24 adults aged 30-65 who are overweight or have obesity. Participants will take the med…

This study tests whether adding a steroid (hydrocortisone) and a powerful antibiotic combination to standard care can help more people with HIV survive sepsis, a life-threatening infection. The trial will enroll 344 adults in Africa who have sepsis and HIV. The goal is to find a …

This early-phase study tests whether a special ultrasound with a targeted contrast agent (Sonazoid) can quickly diagnose heart inflammation caused by immune checkpoint inhibitor cancer drugs. About 30 adults who recently received these drugs and show signs of heart inflammation w…

This study checks if a new portable ankle tester can reliably measure joint looseness in people with healthy ankles, past sprains, or chronic ankle instability. Researchers will also test it on people with fresh ankle sprains over their first month of recovery. The goal is to see…

This study tests different combinations of an online program called CARRII to help Native women reduce their risk of alcohol-exposed pregnancy. 512 women who drink alcohol and are at risk for pregnancy will use the program for 3 months. The goal is to find the most effective and …

This study looks at 10 adults over 50 with hearing loss in both ears and a weak balance system on one side. Researchers want to see if putting a cochlear implant in the ear with worse balance leads to less dizziness after surgery. Participants are randomly assigned to get the imp…

This study looks at whether giving antibiotics to malnourished infants under 1 year old with diarrhea caused by certain viruses or parasites harms their immune system's ability to fight off future infections. Researchers will compare infants who receive usual care (including anti…