University Of Massachusetts, Worcester

This study tests whether personalized text messages can motivate people living with HIV in Vietnam to quit smoking. Participants receive motivational texts over six months and are encouraged to use a free government quitline that provides nicotine patches. The goal is to see if t…

This study tests a clinic program called ActivityChoice that helps cancer survivors become more physically active to lower their risk of heart disease. About 114 adult cancer survivors will be offered a choice of group in-person, group virtual, or self-monitored digital exercise …

This study is testing two mobile health tools—a computer-delivered program and motivational text messages—to help young adults (ages 18-24) in Zambia better manage their HIV and cut down on alcohol use. The goal is to see if these tools are easy to use and acceptable to participa…

This study tests whether a special anti-inflammatory diet, adapted to include traditional Puerto Rican foods, can help people with Crohn's disease feel better and reduce gut inflammation. About 150 adults with mild to moderate Crohn's will follow either the diet or their usual ea…

This study compares two ways to help people with both substance use and mental health disorders: a full team-based program called MISSION that provides counseling, peer support, and community outreach for 6 months, versus just linking them with a peer specialist. Researchers hope…

This study tests whether a computer alert in doctors' charts can help more atrial fibrillation patients get blood thinners to prevent strokes. About 5,094 patients and their doctors are involved. The alert fires during visits if a patient has high stroke risk but isn't on blood t…

This study tests whether interactive storytelling modules can help adults in a large Vietnamese city better control their high blood pressure. Seven hundred participants with uncontrolled hypertension will receive the storytelling intervention or usual care. The goal is to see if…

This study tests a tablet-based app called Jaspr that helps adults with suicidal thoughts while they wait in the emergency department. The app guides users through suicide risk assessment and safety planning based on proven therapies. Researchers will track whether it reduces sui…

This study looks at whether a team of clinical pharmacists and community health workers can help people with type 2 diabetes improve their blood sugar levels using continuous glucose monitors (CGMs). About 318 adults aged 25-75 with high blood sugar will be enrolled. The goal is …

This study is testing a computer-based program called MES-PrEP to help young transgender women in Thailand start and stick with HIV pre-exposure prophylaxis (PrEP). The program provides personalized feedback and information based on each person's confidence and motivation. Resear…

This study looks at two medicines given before surgery to prevent delirium (confusion and agitation) in children aged 3 months to 9 years. One is a nose spray (dexmedetomidine), the other is a syrup (midazolam). The goal is to see which works better and is easier for kids to take…

This study tests a cognitive behavioral therapy (CBT) group designed specifically for women Veterans who have alcohol use disorder. About 162 women will take part, and the therapy focuses on changing drinking habits and related behaviors. The goal is to see if this female-only ap…

This study tests whether special computer-based brain exercises can improve memory, concentration, and thinking in breast cancer survivors who have ongoing mental fogginess after chemotherapy. About 50 women aged 35 to 80 who finished chemo 1 to 8 years ago will either do the bra…

This study tests whether a procedure called radiofrequency ablation can safely reduce chronic knee pain in people who still have pain at least a year after total knee replacement. Fourteen participants will either get the real procedure or a sham version, and researchers will che…

This study tests whether training primary care providers on how to talk to patients about vaccines can increase flu and COVID-19 vaccination rates. Over 24,500 patients and their doctors at multiple clinics will take part. Doctors in some clinics will receive special communicatio…

This study adapts a 'Health at Every Size' program for pregnant people with a BMI over 30. Ten first-time mothers will attend group sessions on nutrition, movement, and self-advocacy. The goal is to see if the program is acceptable and helpful in reducing weight stigma and improv…

This study tests a program called WE CARE in the NICU, which screens families of preterm babies for unmet social needs like housing or job insecurity and provides referrals to community resources. About 882 mothers and their preterm infants (born before 34 weeks) will take part. …

This pilot study tests a program called FIX-SDM that helps patients and their primary care providers talk about lung cancer screening. The program gives providers training and materials, and patients receive a smoking history survey, a decision aid, and text messages before their…

This study tests whether watching storytelling videos can help African American and Black patients with atrial fibrillation (an irregular heartbeat) start and continue taking blood thinners to prevent strokes. About 80 adults who are not currently on blood thinners but have a hig…

This study compares two methods to close the large vein used for implanting a leadless pacemaker: a special closure device versus a figure-of-eight stitch with manual pressure. Researchers will measure how quickly bleeding stops and how soon patients can go home. The goal is to f…

This study tests a new mobile app that uses an avatar guide to help young adults (ages 18-29) who struggle with binge drinking and suicidal thoughts. The goal is to see if the app is easy to use and if people will stick with it. Ten participants from the emergency department will…

This study is building a large national registry of 30,000 people having hip or knee replacement surgery. Researchers will collect information on pain, physical function, and any complications before and after surgery. The goal is to learn what works best in real-world practice a…

This study looks at ways to help mothers of preterm or low birth weight infants in rural India continue Kangaroo Care (skin-to-skin contact) at home after leaving the hospital. Researchers will work with 190 mothers and healthcare providers to understand what support is needed. T…

This study looks at whether using the Huckleberry sleep app can improve infant sleep and the mental health of mothers. Researchers will track 120 families with babies up to 12 months old. They will measure sleep quality, maternal mood, and bonding. The goal is to understand if di…