University Of Massachusetts, Worcester
Clinical trials sponsored by University Of Massachusetts, Worcester, explained in plain language.
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Can better support prevent overdose? new study tests two approaches
Disease control OngoingThis study compares two ways to help people with both substance use and mental health disorders: a full team-based program called MISSION versus working with a Peer Specialist. Researchers will track which approach leads to better treatment engagement, less substance use, and imp…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 16, 2026 23:53 UTC
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New alert system aims to boost stroke prevention in AF patients
Disease control ENROLLING_BY_INVITATIONThis study tests a computer alert that reminds doctors to prescribe blood thinners for patients with atrial fibrillation, a heart condition that raises stroke risk. About 5,000 patients and their doctors are taking part. The goal is to see if the alert helps more patients start a…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 16, 2026 23:51 UTC
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New program helps cancer survivors fight heart disease with exercise
Disease control ENROLLING_BY_INVITATIONThis study tests a clinic-based program called ActivityChoice that helps cancer survivors become more physically active to lower their risk of heart disease. About 114 adult cancer survivors will be offered a choice of group in-person, group virtual, or self-monitored digital exe…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 15, 2026 11:58 UTC
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Phone apps aim to boost HIV care and cut drinking among zambian youth
Disease control OngoingThis study adapts mobile health tools to help 164 young adults (ages 18-24) in Zambia who are living with HIV and struggling with medication adherence and alcohol use. Participants will use a smartphone app and receive motivational text messages to support self-management. The go…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Can a support team help you master your blood sugar?
Disease control ENROLLING_BY_INVITATIONThis study looks at whether support from clinical pharmacists and community health workers can help people with type 2 diabetes better manage their blood sugar using continuous glucose monitors (CGMs). About 318 adults aged 25-75 with high blood sugar will be enrolled. The goal i…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Could a puerto rican diet tame Crohn's Flare-Ups?
Disease control OngoingThis study tests whether a diet designed for Puerto Ricans with Crohn's disease can improve quality of life and reduce gut inflammation. About 150 adults with mild to moderate Crohn's will follow either the special diet or their usual diet for several weeks. The goal is to see if…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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Can stories lower blood pressure? new study in vietnam aims to find out
Disease control ENROLLING_BY_INVITATIONThis study tests whether a storytelling program can help adults in a large city in northern Vietnam better control their high blood pressure. Researchers will enroll 700 adults with uncontrolled hypertension and compare those who receive the storytelling intervention to those who…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 11, 2026 20:49 UTC
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Phone apps could boost HIV prevention in vulnerable youth
Prevention OngoingThis study tests whether smartphone-based tools can help young transgender women in Thailand start and stick with HIV pre-exposure prophylaxis (PrEP). About 145 participants aged 16-29 will use mobile interventions and be followed for 6 months. The goal is to see if these digital…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated May 11, 2026 20:38 UTC
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New study aims to speed up recovery after pacemaker implant
Symptom relief ENROLLING_BY_INVITATIONThis study compares two methods to close the large vein used for a leadless pacemaker implant: a special stitch device versus manual pressure with a figure-of-eight stitch. The goal is to see which stops bleeding faster and helps patients leave the hospital sooner. About 50 adult…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 16, 2026 23:51 UTC
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New therapy for women veterans aims to curb problem drinking
Symptom relief OngoingThis study tests a cognitive behavioral therapy (CBT) group designed specifically for women veterans who have alcohol use disorder. About 162 women will take part, and the therapy focuses on changing thoughts and behaviors around drinking. The goal is to help them drink less and …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 16, 2026 23:47 UTC
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Brain games may beat chemo brain fog
Symptom relief OngoingThis study tests if a computer-based brain training program can help breast cancer survivors who have memory and thinking problems after chemotherapy (chemo brain). About 50 survivors will either do the brain training or receive education for 6 weeks. The goal is to see if the tr…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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ER tablet program aims to cut suicide risk in thousands
Symptom relief ENROLLING_BY_INVITATIONThis study tests a digital platform called Jaspr Health for adults who come to the emergency department with suicidal thoughts or behaviors. The platform provides evidence-based suicide prevention tools during waiting time. About 28,000 participants will be followed for 12 months…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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New hope for lasting knee pain after replacement?
Symptom relief OngoingThis study tests whether a procedure called radiofrequency ablation can safely reduce chronic knee pain in people who still have pain at least one year after knee replacement surgery. Fourteen participants receive either the real treatment or a sham procedure, and are followed fo…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Avatar app aims to curb binge drinking and suicidal thoughts in young adults
Symptom relief OngoingThis study is testing a new smartphone app that uses a friendly avatar guide to help young adults (ages 18-29) who struggle with binge drinking and suicidal thoughts. The goal is to see if the app is easy to use and if people will stick with it for a month. Ten participants from …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC
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New program aims to boost lung cancer screening through shared decisions
Knowledge-focused ENROLLING_BY_INVITATIONThis pilot study tests a program called FIX-SDM that helps patients and their primary care doctors talk about and decide on lung cancer screening. About 120 patients and their doctors will take part. The goal is to see if the program increases the number of people who get screene…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 16, 2026 23:38 UTC
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Skin-to-Skin care goes home: new study supports rural indian mothers of preterm babies
Knowledge-focused OngoingThis study aims to help mothers of preterm or low birth weight infants continue Kangaroo Care (skin-to-skin contact) at home after leaving the hospital in rural India. Researchers will work with 190 mothers and healthcare providers to develop and test ways to support this practic…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Can an app help babies sleep better and moms feel less stressed?
Knowledge-focused OngoingThis study looks at whether using the Huckleberry sleep app helps babies sleep better and improves mothers' mental health. About 120 mothers with infants under 1 year old will answer surveys about sleep, mood, and bonding. The goal is to understand if digital tools can support fa…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Storytelling may boost blood thinner use in black heart patients
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether watching storytelling videos can help African American and Black patients with atrial fibrillation (an irregular heartbeat) start and continue taking blood thinners to prevent strokes. About 80 adults who are not currently on blood thinners but should be …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC
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Can a body-positive approach improve mental health in pregnancy?
Knowledge-focused OngoingThis study aims to adapt a Health at Every Size (HAES) program for pregnant people with a BMI over 30. Weight stigma during pregnancy may increase the risk of depression and anxiety. Researchers will work with 10 first-time pregnant individuals to design and test a group program …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC
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Massive 30,000-Patient study aims to improve joint replacement safety nationwide
Knowledge-focused OngoingThis study is creating a national registry to track the long-term results of hip and knee replacement surgeries. It will follow 30,000 patients from diverse backgrounds to understand what leads to better pain relief, function, and fewer complications after surgery. The goal is to…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Apr 20, 2026 16:17 UTC