Can a phone app boost HIV prevention in thai youth?

NCT ID NCT05262426

Ongoing Prevention Sponsor: University of Massachusetts, Worcester Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a computer-based program called MES-PrEP to help young transgender women in Thailand start and stick with HIV pre-exposure prophylaxis (PrEP). The program provides personalized feedback and information based on each person's confidence and motivation. Researchers will measure how acceptable and easy to use the program is, and whether it improves PrEP adherence over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Motivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP) – a computer-delivered behavioral intervention
What this could lead to: If successful, this could provide an effective, scalable way to boost PrEP use among at-risk youth, helping prevent HIV infections.
What could go wrong: This is an early feasibility study with only 145 participants, so results may not apply broadly. The intervention relies on self-reported adherence, which can be inaccurate.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRE EXPOSURE PROPHYLAXIS

Contacts and locations

Locations

Institute of HIV Research and Innovation

Bangkok, Bangkok, 10330, Thailand
Rainbow Sky Association of Thailand

Bangkok, Bangkok, 10240, Thailand
SWING Foundation

Bangkok, Bangkok, 10500, Thailand

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