Can food vouchers and peer support keep women on HIV prevention pills?

NCT ID NCT06274060

First seen May 09, 2026 · Last updated Jun 23, 2026 · Updated 7 times

Summary

This completed trial in South Africa tested four support strategies—case management, food vouchers, peer buddies, and community PrEP pick-up points—to help female sex workers and young women stay on PrEP, a daily pill that prevents HIV. 304 participants were randomly assigned to different combinations of these strategies. The goal was to see which approaches best encourage long-term PrEP use, so these services can be expanded to other districts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • TB HIV Care

    Pietermaritzburg, KwaZulu-Natal, 3200, South Africa

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

case management, food vouchers, peer support buddies, community-based PrEP pick-up points

What this could lead to

If successful, this could identify the best support strategies to help women at high risk for HIV consistently take PrEP, potentially reducing new HIV infections in South Africa.

What could go wrong

This is a completed phase 2b trial with 304 participants, so results may not apply to all women or regions. The strategies may not work as well outside the study setting.

Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.