Heat treatment for Post-Replacement knee pain put to the test

NCT ID NCT05473663

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a procedure called radiofrequency ablation can safely reduce chronic knee pain in people who still have pain at least a year after total knee replacement. Fourteen participants will either get the real procedure or a sham version, and researchers will check if they feel better after 3 months. The goal is to see if this treatment is worth offering more widely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiofrequency ablation (a procedure using heat to deaden nerves around the knee)

What this could lead to

If it works, this could offer a non-surgical option for people with lingering knee pain after a knee replacement.

What could go wrong

This is a very small, early study with only 14 participants. The procedure may not provide lasting relief, and there are risks like infection or nerve damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Massachusetts Chan Medical School

    Worcester, Massachusetts, 01655, United States