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Ultrasound measurements may predict who benefits from knee pain block

NCT ID NCT07712419

Knowledge-focused Sponsor: Gaziosmanpasa Research and Education Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Aug 18, 2026 · Updated 2 times

Summary

This study looks at whether ultrasound measurements of thigh muscle and fat can predict how well patients with knee osteoarthritis respond to a genicular nerve block. Researchers will measure muscle thickness and fat under the skin before the procedure and check pain levels one month later. The goal is to find simple imaging clues that help doctors choose the best treatment for each patient.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound-Guided Genicular Nerve Block
What this could lead to
If successful, this could help doctors identify which patients with knee osteoarthritis are most likely to benefit from genicular nerve block, improving treatment selection.
What could go wrong
This is a small observational study, so results may not apply to all patients. The ultrasound measurements may not reliably predict pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults with symptomatic bilateral Kellgren-Lawrence grade 3-4 knee osteoarthritis referred from the Department of Physical Medicine and Rehabilitation to the Pain Medicine Clinic for ultrasound-guided genicular nerve block after failure of conservative treatment. Consecutive eligible patients meeting the inclusion criteria will be enrolled prospectively.

Ages

45 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥45 years. * Symptomatic bilateral knee osteoarthritis with Kellgren-Lawrence grade 3 or 4. * Visual Analog Scale (VAS) pain score ≥4 at rest or during movement. * Scheduled to undergo first ultrasound-guided genicular nerve block. * No intra-articular knee injection within the previous 3 months. * Considered unsuitable for or awaiting total knee arthroplasty. * Ability to provide written informed consent. Exclusion Criteria: * Inflammatory arthritis, rheumatoid arthritis, or crystal arthropathy. * Previous knee surgery or knee prosthesis. * Active local or systemic infection. * Anticoagulant therapy or bleeding disorders. * Contraindication to corticosteroids (including uncontrolled diabetes mellitus). * Allergy to study medications. * Neurological disorders causing neuropathic knee pain. * Dementia or inability to complete study assessments. * Additional interventional procedures or surgery during follow-up.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic knee pain Knee osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Health Sciences Gaziosmanpaşa Physical Therapy and Rehabilitation Training and Research Hospital

    RECRUITING

    Istanbul, 34255, Turkey (Türkiye)

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