Could a tiny nerve zap ease stubborn knee arthritis pain?

NCT ID NCT07703293

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study looks at whether adding a targeted nerve treatment to a standard procedure can better relieve chronic knee pain from osteoarthritis. Researchers are comparing standard radiofrequency treatment alone versus standard treatment plus pulsed radiofrequency on specific sensory nerve branches in the knee. Adults aged 45 to 80 with knee osteoarthritis and persistent pain despite other treatments are being followed for three months to measure changes in pain and function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pulsed radiofrequency treatment of distal sensory branches of the nerve to vastus medialis
What this could lead to
If successful, this approach could provide better pain relief and improved knee function for people with chronic knee osteoarthritis who haven't responded to standard treatments.
What could go wrong
This is a small observational study, so results may not apply to everyone. The added treatment might not provide significant benefit over the standard procedure, and there are always risks like nerve damage or infection.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ayse Betul Acar

    RECRUITING

    Ankara, 06500, Turkey (Türkiye)

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