University Of Massachusetts, Worcester
Clinical trials sponsored by University Of Massachusetts, Worcester, explained in plain language.
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Could a common diabetes drug help fight TB in HIV patients?
Disease control CompletedThis study looked at whether adding metformin, a diabetes drug, to standard tuberculosis (TB) treatment is safe and tolerable for people also living with HIV. 112 adults with TB and HIV took either standard TB medicines alone or with metformin for 11 weeks. Researchers monitored …
Phase: PHASE2 • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Fitbit and coaching: a new boost for weight loss drug users?
Disease control CompletedThis study tested whether a Fitbit activity tracker combined with virtual health coaching could help people on weight loss medications (GLP-1/GIP) become more active. Fifteen participants wore a Fitbit and had up to six coaching sessions over 12 weeks. The main goal was to see if…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Breast MRI showdown: which contrast agent is better?
Diagnosis CompletedThis study compared two MRI contrast agents, Dotarem and Gadavist, in 300 women undergoing breast MRI. The goal was to see if Dotarem is as effective as Gadavist at enhancing breast lesions for clearer images. Participants were randomly assigned to receive one of the two agents, …
Phase: PHASE4 • Sponsor: University of Massachusetts, Worcester • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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Phone tools help young thai men stick with HIV prevention
Prevention CompletedThis study tested whether mobile health tools (like text messages and apps) can help young Thai men who have sex with men start and keep taking HIV pre-exposure prophylaxis (PrEP). 119 HIV-negative men aged 16-25 at risk for HIV took part. Researchers measured how acceptable and …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated Jun 27, 2026 09:11 UTC
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Texting program aims to lower depression risk in new moms
Symptom relief CompletedThis study tested a text messaging program designed to reduce the risk of major depression in pregnant and postpartum women. The program sent tailored texts with links to videos and a chat feature where participants could talk with each other. The study included 40 women who were…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Music may keep hospitalized Parkinson's patients Clear-Headed
Symptom relief CompletedThis study tested whether music therapy can prevent hospital-related confusion (delirium) in people with Parkinson's disease or Lewy body dementia. 30 hospitalized adults took part, receiving either music therapy sessions, self-directed music listening, or standard care. Research…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Teens help teens kick the vape habit in new texting study
Symptom relief CompletedThis study tested a program called Vaper-to-Vaper (V2V) that uses peer messages, text coaching, and gamification to help teenagers quit vaping. 71 high school students who currently used e-cigarettes took part. The goal was to see if teens would join and stay in the program, and …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated Jun 26, 2026 13:40 UTC
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Can a video call save lives? telehealth tested in ERs for suicide prevention
Knowledge-focused CompletedThis study tested whether using telehealth (video calls) to connect emergency room patients with mental health experts can improve suicide prevention. Over 32,000 adults in Massachusetts took part. The goal was to see if this approach leads to better risk assessments and fewer un…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New app aims to ease tough choices for brain injury families
Knowledge-focused CompletedThis pilot study tested a web-based tool designed to improve communication and decision-making between doctors and families of patients with severe acute brain injuries, such as stroke or traumatic brain injury. The tool helps prepare families for their role as decision-makers an…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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AI assists in tricky gallbladder procedure
Knowledge-focused CompletedThis study tested a new artificial intelligence (AI) tool designed to help doctors safely drain an infected gallbladder in patients who cannot have surgery. The AI was used during an endoscopic ultrasound procedure to guide placement of a special stent. Researchers compared the A…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Alzheimer's caregivers get help to cut dangerous pills
Knowledge-focused CompletedThis study tested whether mailing educational materials to caregivers of people with Alzheimer's could reduce the use of risky medications like sedatives and antipsychotics. Over 11,000 older adults with Alzheimer's took part. The goal was to see if this simple approach could mak…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New online tool aims to end confusion for osteoarthritis patients facing surgery
Knowledge-focused CompletedThis study tested a personalized web-based care plan for over 5,700 adults with knee or hip osteoarthritis. The goal was to help patients and their doctors make more informed decisions about treatments, including whether to have joint replacement surgery. The study measured how w…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Study tests best way to warn young adults about vaping dangers
Knowledge-focused CompletedThis study looked at how to present e-cigarette education messages to young adults ages 18-24 who vape or are at risk of starting. Researchers tested different message sources (expert vs. peer) and presentation styles (one-sided vs. two-sided) to see which was most accepted and i…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Phone and video calls boost lung cancer screening follow-up in small pilot
Knowledge-focused CompletedThis study tested whether telehealth coaching can help people get their yearly lung cancer screening on time. 22 participants who were overdue for a follow-up low-dose CT scan received coaching via video or phone call. The goal was to see if this approach is practical and helps p…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Bias training for doctors may lower blood pressure in minority patients
Knowledge-focused CompletedThis study tested whether a training program called CONSULT-BP, which teaches healthcare trainees to recognize bias and communicate better, could improve blood pressure in their patients with hypertension. The study included 118 patients, mostly from minority or low-income backgr…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:06 UTC
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Could a simple arm cuff replace the need for an artery needle during surgery?
Knowledge-focused CompletedThis study tested a wearable, non-invasive blood pressure monitor called ViTrack against the standard method of placing a small tube in the wrist artery. Researchers compared blood pressure readings from 30 surgery or ICU patients at 255 time points. The goal was to see if the cu…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:25 UTC
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Can a Face-Reading computer task help understand anxiety?
Knowledge-focused CompletedThis study looked at how people with high anxiety process emotional faces, since they often struggle to tell safe from threatening situations. Twenty-three young adults completed brain scans and some returned months later for a computer training task that teaches them to spot tin…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:25 UTC