University Of Massachusetts, Worcester
Clinical trials sponsored by University Of Massachusetts, Worcester, explained in plain language.
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ER video calls aim to transform suicide prevention
Disease control CompletedThis study tested whether using video calls to connect emergency room patients at risk for suicide with mental health specialists could improve their care. It involved over 32,000 adults in Massachusetts emergency rooms. The goal was to see if this approach provided better, faste…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Phone calls for prevention: telehealth aims to keep At-Risk patients on track for cancer scans
Disease control CompletedThis study tested a telehealth support program to help people complete their recommended annual follow-up scans for lung cancer screening. Researchers worked with patients and healthcare providers to design the program, then offered it to a small pilot group. The main goal was to…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Doctors test fitbit & coach combo to boost activity for patients on new Weight-Loss drugs
Disease control CompletedThis small study tested a program to help people on weight-loss medications (like Ozempic or Wegovy) become more physically active. Fifteen patients received a Fitbit and worked with a health coach for 12 weeks. The main goal was to see if this combined approach was practical and…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Teens texting teens to kick the vaping habit
Disease control CompletedThis study tested a new mobile app called Vaper-to-Vaper (V2V) designed to help high school students quit using e-cigarettes. The program used peer texting, coaching, and game-like features to teach teens strategies to manage cravings and quit vaping. Researchers worked with 71 s…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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Doctors get special training to better connect with patients, lower blood pressure
Disease control CompletedThis study tested a training program for doctors-in-training and nurse practitioner students to improve how they communicate with and care for minority and low-income patients with high blood pressure. The goal was to see if this training would help patients achieve lower blood p…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Diabetes drug tested to fight TB and protect lungs in HIV patients
Disease control CompletedThis study tested whether adding the common diabetes medication metformin to standard antibiotic treatment for tuberculosis (TB) is safe and helps people recover better, especially for those also living with HIV. Researchers wanted to see if metformin could help clear the TB infe…
Phase: PHASE2 • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 16, 2026 15:25 UTC
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Mailbox medicine: simple letters aim to slash dangerous drug use in Alzheimer's patients
Disease control CompletedThis study tested whether sending educational mail to caregivers and doctors could reduce the use of potentially harmful medications in people with Alzheimer's disease. Over 11,000 patients living at home who were taking risky drugs like sedatives or antipsychotics were part of t…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated Mar 10, 2026 12:52 UTC
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Wrist band aims to replace needle for blood pressure monitoring
Diagnosis CompletedThis study tested a new wrist-worn device that measures blood pressure continuously without needing a needle in the artery. Researchers compared its readings to the standard method (an arterial catheter) in 30 patients having surgery or staying in the intensive care unit. The goa…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Diagnosis
Last updated Mar 30, 2026 14:35 UTC
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Study tests if two common MRI dyes give equally clear breast cancer images
Diagnosis CompletedThis study compared two different contrast agents (dyes) used during breast MRI scans to see if one produces clearer images than the other. 300 women scheduled for a breast MRI were randomly assigned to receive either Dotarem or Gadavist. Radiologists then reviewed the scan image…
Phase: PHASE4 • Sponsor: University of Massachusetts, Worcester • Aim: Diagnosis
Last updated Mar 30, 2026 14:33 UTC
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Texting away the baby blues: simple messages aim to stop depression before it starts
Prevention CompletedThis study tested whether a simple text messaging program could help prevent depression in pregnant women and new mothers. Researchers sent daily supportive texts, links to helpful videos, and offered a chat with a trained peer to 40 participants who were at risk for depression. …
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated Mar 31, 2026 12:12 UTC
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Phone app aims to boost HIV prevention pill use among young thai men
Prevention CompletedThis study tested whether a mobile app and supportive text messages could help young Thai men who have sex with men start taking and consistently using HIV prevention pills (PrEP). 119 participants were randomly assigned to receive either the app and texts plus standard counselin…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Personalized playlists fight hospital confusion in brain disease patients
Prevention CompletedThis small pilot study tested whether music therapy could prevent delirium (sudden confusion) in hospitalized patients with Parkinson's disease or Lewy body dementia. Thirty patients were randomly assigned to receive either personalized music therapy sessions, generic music playl…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Prevention
Last updated Mar 27, 2026 12:38 UTC
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Scientists crowdsource best way to warn young adults about vaping dangers
Knowledge-focused CompletedThis study aimed to discover which types of anti-vaping public health messages work best for young adults. Researchers tested messages from different sources (experts vs. peers) and in different formats (one-sided vs. two-sided arguments) with 848 young adults aged 18-24. The goa…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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New online tool aims to help arthritis patients decide on surgery
Knowledge-focused CompletedThis study tested a web-based, personalized care plan to help people with knee or hip osteoarthritis make better-informed decisions about their treatment. Over 5,700 patients worked with their doctors to use this tool, which provided information on pain trends, treatment options,…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists scan anxious brains to see how they read emotions
Knowledge-focused CompletedThis study aimed to understand how people with high levels of anxiety process emotional faces, like fear or happiness. Researchers used brain scans (MRI) and computer tasks where participants identified facial expressions. The goal was to gather basic science information that cou…
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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AI steps into the operating room to guide gallbladder drainage
Knowledge-focused CompletedThis study tested a new artificial intelligence (AI) tool designed to help doctors safely place a small metal tube (stent) to drain an infected gallbladder. The procedure is for patients with cholecystitis who are too sick for surgery. Researchers compared the AI's safety recomme…
Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC