University Hospital Heidelberg

This study is comparing two different radiation treatments for patients with 4-15 brain metastases (cancer that has spread to the brain). It aims to see if a more targeted, shorter treatment (CyberKnife radiosurgery) is as effective as the standard whole-brain radiation, while po…

This study is for adults newly diagnosed with a specific type of brain tumor called an oligodendroglioma. It aims to find out if starting with a newer combination of chemotherapy drugs (CETEG) and delaying radiation therapy is better than the current standard treatment of radiati…

This study is testing two types of advanced radiation therapy (protons or carbon ions) given before surgery for abdominal soft tissue sarcoma. The main goal is to see if these treatments are safe and cause fewer severe side effects to nearby organs compared to standard radiation.…

This study is testing whether adding a spinal drain to the standard brain drain helps people recover better after a severe brain bleed that fills the brain's fluid spaces. Researchers want to see if this two-drain approach clears blood faster, improves functional outcomes, and re…

This study is testing a targeted form of radiation called proton beam therapy for women whose breast cancer has returned in the same breast after previous surgery and radiation. The goal is to see if this precise treatment can effectively control the returning cancer while causin…

This study is testing whether lying flat on your back for 5 days after a specific type of corneal transplant (DMEK) helps the new tissue attach better to the eye compared to lying down for just 1 day. Researchers will enroll 102 people with Fuchs' dystrophy and randomly assign th…

This study is testing a specialized type of radiation called carbon ion re-radiotherapy for people whose head and neck cancer has come back or progressed after initial treatment. It aims to see if this approach can control the cancer while causing fewer severe side effects compar…

This study is testing if a new, more precise type of radiation therapy can better control cancer that has spread to the liver while causing fewer side effects. It will compare MRI-guided radiation, which uses real-time imaging to target tumors more accurately, against the current…

This study is testing a new, shorter radiation treatment for soft tissue sarcoma in the arms or legs. It aims to see if using targeted proton or carbon ion radiation for 2-3 weeks before surgery is safe and causes fewer wound healing problems than the standard 5-week treatment. T…

This study is testing a new approach for early-stage, low-risk breast cancer. It compares a single dose of radiation given right during surgery to the standard treatment of weeks of daily radiation afterward. The main goal is to see if the one-time treatment causes less fatigue w…

This study is testing if adding a probiotic lozenge, or a probiotic plus vitamin B12 drops, to standard dental cleaning helps improve the community of bacteria in the mouth for people with serious gum disease (periodontitis). Sixty adults will receive either standard care alone, …

This study is testing if a newer type of radiation (proton beams) causes fewer side effects than standard radiation (photon beams) for people with glioblastoma, a serious brain cancer. About 326 adults with this cancer will be randomly assigned to receive one of the two radiation…

This study is testing whether a newer type of radiation (proton therapy) causes fewer bowel side effects than standard radiation (photon therapy) for men who need radiation after prostate cancer surgery. It also checks if a shorter, more intense radiation schedule works as well a…

This study is testing whether advanced PET scans can more accurately map the borders of early-stage esophageal cancer. Researchers will compare scan results from 30 patients to tissue samples taken during surgery. The goal is to see if better imaging could allow doctors to target…

This study is testing a personalized exercise program designed to prevent falls in people being treated for multiple myeloma, a type of blood cancer. Researchers want to understand what makes these patients more likely to fall and see if regular strength and balance training can …

This study is exploring whether tiny particles in the blood, called extracellular vesicles, can act as a 'liquid biopsy' to monitor meningioma brain tumors. Researchers will track these particles in 60 patients before, during, and after radiation therapy to see if changes in the …

This study is testing if a special type of MRI scan can better see and track different forms of Interstitial Lung Disease (ILD), a group of conditions that cause lung scarring. Researchers will compare the MRI results to standard CT scans to see if it can more clearly show diseas…