Proton beams may ease brain tumor treatment side effects

NCT ID NCT04752280

Recruiting now Symptom relief Sponsor: University Hospital Heidelberg Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether proton beam radiation causes fewer side effects than standard photon radiation in people with glioblastoma, an aggressive brain cancer. About 326 patients will receive either proton or photon therapy alongside standard care. The main goal is to see if proton therapy reduces early toxicities within the first four months, while also tracking survival and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Proton beam radiation
What this could lead to: If successful, this could show that proton therapy causes fewer short-term side effects than standard photon radiation for glioblastoma patients.
What could go wrong: This trial focuses on reducing side effects, not on curing the disease. The overall prognosis for glioblastoma remains poor, and the benefit may be limited to early toxicity reduction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GLIOBLASTOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOBLASTOMA

Contacts and locations

Locations

Klinikum Stuttgart
NOT_YET_RECRUITING

Stuttgart, Germany
Universitätsklinikum Gießen und Marburg
NOT_YET_RECRUITING

Marburg, Germany
Universitätsklinikum Heidelberg
RECRUITING

Heidelberg, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.