Gum disease breakthrough? probiotics and B12 under the microscope
NCT ID NCT07443410
First seen Mar 15, 2026 · Last updated Jun 16, 2026 · Updated 12 times
Summary
This study looks at whether taking probiotics (with or without vitamin B12) can improve the health of the mouth's bacteria and reduce gum disease in adults with severe periodontitis. Participants will receive standard gum treatment plus either a probiotic lozenge, a probiotic with vitamin B12 drops, or no supplement for 3 months. The goal is to see if these supplements help the standard treatment work better by changing the bacteria in the mouth.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Heidelberg University Hospital
RECRUITINGHeidelberg, Baden-Wurttemberg, 69120, Germany
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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