Gum disease breakthrough? probiotics and B12 under the microscope

NCT ID NCT07443410

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether taking probiotics (with or without vitamin B12) can improve the health of the mouth's bacteria and reduce gum disease in adults with severe periodontitis. Participants will receive standard gum treatment plus either a probiotic lozenge, a probiotic with vitamin B12 drops, or no supplement for 3 months. The goal is to see if these supplements help the standard treatment work better by changing the bacteria in the mouth.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Heidelberg University Hospital

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

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