Can deep cleaning reverse Smoking's toll on gum disease?
NCT ID NCT06351722
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study looks at how smoking and gum disease (periodontitis) affect certain proteins and genetic markers in the body. Researchers will compare these markers in smokers and non-smokers with and without gum disease, before and after a standard deep-cleaning treatment. The goal is to understand the biological links between smoking, gum disease, and inflammation, which could lead to better ways to manage gum health in smokers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Non-surgical periodontal treatment (deep cleaning)
- What this could lead to
- If successful, this could reveal how smoking affects the body's inflammatory response to gum disease and whether treatment can reverse those effects, potentially guiding better care for smokers.
- What could go wrong
- This is an observational study, so it can't prove cause and effect. The results may not apply to everyone, and the biomarkers measured may not directly reflect clinical outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Necmettin Erbakan University Faculty of Dentistry, Department of Periodontology
Konya, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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