Can a common drug mend a broken heart? new trial aims to find out
NCT ID NCT05946772
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if the drug cyclosporine can reduce heart muscle damage in people with Takotsubo syndrome, also known as broken heart syndrome. About 204 adults at high risk for complications will receive either cyclosporine or a placebo shortly after diagnosis. Researchers will measure heart injury and function over one year to see if the drug helps the heart recover better.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cardiovascular Centre - University Hospital Düsseldorf
RECRUITINGDüsseldorf, Germany
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Department of Cardiology - University Hospital Essen
RECRUITINGEssen, Germany
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Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin
RECRUITINGBerlin, Germany
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Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum
RECRUITINGBerlin, Germany
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Department of Cardiology, Heidelberg University Hospital
RECRUITINGHeidelberg, 69120, Germany
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Department of Cardiology, Hospital of the Ludwig-Maximilians-University Munich
RECRUITINGMünchen, Germany
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Department of Cardiology, University Hospital Dresden
RECRUITINGDresden, Germany
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Department of Cardiology, University Hospital Frankfurt
RECRUITINGFrankfurt, Germany
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Department of Cardiology, University Hospital Halle
RECRUITINGHalle, Germany
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Department of Cardiology, University Hospital Köln
RECRUITINGCologne, Germany
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Department of Cardiology, University Hospital Leipzig
RECRUITINGLeipzig, Germany
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Department of Cardiology, University Hospital Magdeburg
RECRUITINGMagdeburg, Germany
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Department of Cardiology, University Hospital Mainz
RECRUITINGMainz, Germany
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Department of Cardiology, University Hospital Mannheim
RECRUITINGMannheim, Germany
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Department of Cardiology, University Hospital Rostock
RECRUITINGRostock, Germany
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Department of Cardiology, University Hospital Ulm
RECRUITINGUlm, Germany
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Department of Cardiology, University Hospital Wuppertal
RECRUITINGWuppertal, Germany
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Heart Centre - University Hospital Bonn
RECRUITINGBonn, Germany
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Kerckhoff Heart Center, Bad Nauheim / Gießen University
RECRUITINGBad Nauheim, Germany
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Leipzig Heart Center
RECRUITINGLeipzig, Germany
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University Hospital rechts der Isar, Technical University of Munich
RECRUITINGMünchen, Germany
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University Medical Center Göttingen
RECRUITINGGöttingen, Germany
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University Medical Center Hamburg-Eppendorf
RECRUITINGHamburg, Germany
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University Medical Center Schleswig-Holstein/Campus Lübeck
RECRUITINGLübeck, Germany
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Heart healing from the inside out: resilience training may boost recovery after cardiac events
- Could a virtual support group ease anxiety after 'Broken Heart' syndrome?
- Could your genes make you prone to broken heart syndrome?
- Broken heart syndrome study probes stress triggers
- Scientists use manganese to peek inside 'Broken Hearts'
- Scientists launch largest U.S. registry to unravel broken heart syndrome