Scientists use manganese to peek inside 'Broken Hearts'
NCT ID NCT07491718
First seen Mar 27, 2026 · Last updated Jun 23, 2026 · Updated 14 times
Summary
This study aims to better understand takotsubo cardiomyopathy, also known as broken heart syndrome, by using manganese-enhanced MRI scans. Researchers will test how different heart medications affect manganese uptake in the heart muscle. The study involves 100 adults who have had takotsubo cardiomyopathy and will compare the effects of bisoprolol, valsartan, sacubitril/valsartan, dapagliflozin, or no medication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Edinburgh
RECRUITINGEdinburgh, United Kingdom
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bisoprolol, Valsartan, Sacubitril/Valsartan, Dapagliflozin
What this could lead to
If successful, this could reveal which medications best help the heart recover after takotsubo cardiomyopathy, potentially improving treatment guidelines.
What could go wrong
This is an early-stage observational study with only 100 participants, so results may not apply to all patients. The medications tested are already approved, so no new drug discovery is expected.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.