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Tako-tsubo cardiomyopathy
MONDO:0019018Takotsubo cardiomyopathy (TC) is a recently described acute cardiac syndrome that mimics acute myocardial infarction and is characterized by ischemic chest symptoms, an elevated ST segment on electrocardiogram, and elevated levels of cardiac disease markers.
Also known as: Tako-Tsubo syndrome, Takotsubo Cardiomyopathy, Takotsubo cardiomyopathy, Takotsubo syndrome, ampulla cardiomyopathy, apical ballooning syndrome, ballooning cardiomyopathy, broken heart syndrome
22 clinical trials for this condition and its sub-types.
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Heart healing from the inside out: resilience training may boost recovery after cardiac events
Disease control Recruiting nowThis study tests whether adding resilience training—a mix of group therapy and relaxation exercises—to standard rehabilitation helps people recover from Takotsubo cardiomyopathy (broken heart syndrome) or a recent heart attack. Participants attend two group therapy sessions and t…
Sponsor: Pensionsversicherungsanstalt • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Can a common drug mend a broken heart? new trial aims to find out
Disease control Recruiting nowThis study tests if the drug cyclosporine can reduce heart muscle damage in people with Takotsubo syndrome, also known as broken heart syndrome. About 204 adults at high risk for complications will receive either cyclosporine or a placebo shortly after diagnosis. Researchers will…
Phase 2 • Sponsor: University Hospital Heidelberg • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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A glowing dye could expose hidden heart scarring
Diagnosis Recruiting nowThis study tests whether a new radioactive dye, 68Ga-FAPI, can spot active scarring in the heart muscle using PET-MR scans. Researchers will scan about 290 people with various heart muscle conditions, such as heart failure with preserved ejection fraction, hypertrophic cardiomyop…
Sponsor: University of Edinburgh • Aim: Diagnosis
Last updated Aug 28, 2026 00:00 UTC
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Could a virtual support group ease anxiety after 'Broken Heart' syndrome?
Symptom relief Recruiting nowThis study tests whether joining a virtual support group can help reduce anxiety in people who have had Takotsubo syndrome, also known as 'broken heart syndrome.' Participants meet online every other week for group therapy and education. The goal is to see if this support lowers …
Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Can a heart registry unlock the secrets of broken heart syndrome?
Knowledge-focused Recruiting nowThis study is building a large registry of people diagnosed with Takotsubo cardiomyopathy, a temporary heart condition often triggered by stress. Researchers will collect medical history, health updates, and blood samples to identify different types of the condition, improve diag…
Sponsor: Cedars-Sinai Medical Center • Aim: Knowledge-focused
Last updated Aug 21, 2026 00:00 UTC
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Heart scans may unlock hidden risks in minority communities
Knowledge-focused Recruiting nowThis study is looking at whether advanced heart imaging, especially cardiac MRI, can help identify the cause of cardiomyopathy and predict risks like death or heart failure in a diverse group of patients. The research focuses on adults in the Bronx, including many from Hispanic a…
Sponsor: Montefiore Medical Center • Aim: Knowledge-focused
Last updated Aug 12, 2026 00:00 UTC
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5,000 patients to help unlock secrets of inflammatory heart disease
Knowledge-focused Recruiting nowThis study aims to learn how well heart scans (MRI, ultrasound, PET) can detect and predict outcomes in people with suspected or known inflammatory heart diseases. Researchers will follow 5,000 adults for one year to see how often heart involvement is confirmed and how it affects…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Can stem cells help heal a broken heart? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether CD34+ stem cells, which help maintain tiny blood vessels in the heart, are linked to how well the heart recovers in people with Takotsubo syndrome (also known as broken heart syndrome). Researchers will measure heart function in 40 participants at the …
Sponsor: University Medical Centre Ljubljana • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Could your genes make you prone to broken heart syndrome?
Knowledge-focused Recruiting nowThis study aims to find out if genetics play a role in who gets broken heart syndrome (Takotsubo cardiomyopathy), a condition that mimics a heart attack and is often triggered by intense stress. Researchers will collect blood samples from 700 people diagnosed with the condition i…
Sponsor: University of Aberdeen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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10,000 heart patients join online registry to unlock secrets of cardiomyopathy
Knowledge-focused Recruiting nowThis study is building a large online registry of 10,000 adults with cardiomyopathy or myocarditis, plus those with a strong family history. Researchers will track participants over time to see how many experience serious events like heart failure, dangerous heart rhythms, or dea…
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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AI could help predict sudden cardiac death in hereditary heart disease patients
Knowledge-focused Recruiting nowThis study aims to improve how doctors predict the risk of sudden cardiac death or heart failure in people with inherited heart diseases. Researchers will use artificial intelligence to analyze data from 1,000 participants, including medical history, ECGs, imaging, genetic tests,…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Scientists use manganese to peek inside 'Broken Hearts'
Knowledge-focused Recruiting nowThis study aims to better understand takotsubo cardiomyopathy, also known as broken heart syndrome, by using manganese-enhanced MRI scans. Researchers will test how different heart medications affect manganese uptake in the heart muscle. The study involves 100 adults who have had…
Sponsor: University of Edinburgh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Can we predict who will die suddenly from heart problems?
Knowledge-focused Recruiting nowThis study follows 1500 people who already have an implantable cardioverter-defibrillator (ICD) to prevent sudden cardiac death. Researchers will track heart function, genetics, and blood markers to find better ways to predict who is at highest risk. The goal is to improve how do…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Heart tissue analysis aims to unlock better diagnosis
Knowledge-focused Recruiting nowThis study looks at heart tissue samples from 216 adults who already need a biopsy as part of their care. Researchers want to find unique molecular patterns in different heart conditions, including after a heart transplant. The goal is to improve how these diseases are diagnosed …
Sponsor: University Hospital, Essen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Scientists launch largest U.S. registry to unravel broken heart syndrome
Knowledge-focused Recruiting nowThis study tracks 500 people diagnosed with takotsubo (broken heart) syndrome to better understand what causes it and how it affects patients over time. Researchers will monitor heart events, quality of life, and stress levels through medical records and questionnaires. No new tr…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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500 heart patients join global study to unravel 'Broken Heart' syndrome
Knowledge-focused Recruiting nowThe GEIST registry is an international study collecting information from 500 people with Takotsubo syndrome, also known as 'broken heart syndrome.' Researchers are gathering data on symptoms, test results, treatments, and outcomes to better understand this temporary heart conditi…
Sponsor: Prof. Dr. med. Ingo Eitel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Establishing the incidence of tako-tsubo cardiomyopathy in scotland - the STARR study
Recruiting nowAcute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it has been suggested that the risk of death is similar to a myocardial infarction. The purpose of t…
Sponsor: University of Aberdeen
Last updated Sep 09, 2026 15:00 UTC