Can we predict who will die suddenly from heart problems?

NCT ID NCT00733590

Recruiting now Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 1500 people who already have an implantable cardioverter-defibrillator (ICD) to prevent sudden cardiac death. Researchers will track heart function, genetics, and blood markers to find better ways to predict who is at highest risk. The goal is to improve how doctors decide who needs these life-saving devices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better identify which patients are most at risk of sudden cardiac death and who would benefit most from an ICD.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may take years and might not lead to immediate changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac cardiac rhythm disease cardiomyopathy congestive heart failure Death, Sudden, Cardiac heart failure sudden cardiac arrest sudden arrhythmia death syndrome prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARRHYTHMIA CARDIOMYOPATHIES DEATH, SUDDEN, CARDIAC HEART FAILURE，CONGESTIVE

Contacts and locations

Locations

Johns Hopkins University School of Medicine
RECRUITING

Baltimore, Maryland, 21205, United States
University of Maryland Medical Center
RECRUITING

Baltimore, Maryland, 21201, United States
Virginia Commonwealth University School of Medicine
RECRUITING

Richmond, Virginia, 23298, United States
Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States

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