The University Of Texas Health Science Center At San Antonio
Clinical trials sponsored by The University Of Texas Health Science Center At San Antonio, explained in plain language.
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Could an old malaria drug help fight liver cancer?
Disease control CompletedThis study tested whether adding hydroxychloroquine (a drug used for malaria) to standard sorafenib treatment could better control advanced liver cancer. The idea was to block a process called autophagy that cancer cells use to survive. The trial enrolled 64 adults with liver can…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Gum surgery upgrade: blood concentrate may speed healing and cut pain
Disease control CompletedThis study tested whether adding a substance made from a patient's own blood (L-PRF) to standard gum surgery improves healing and reduces pain. Twenty-one adults with gum disease took part. The researchers compared standard surgery alone to surgery with L-PRF, measuring pocket de…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC
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Can a transplant drug boost heart health in the elderly?
Disease control CompletedThis study looked at whether rapamycin, a drug used to prevent transplant rejection, can improve heart function in healthy adults aged 70-95. Researchers used MRI scans to measure changes in heart pumping and blood vessel flexibility after 8 weeks of treatment. The goal was to se…
Phase: PHASE2 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Disease control
Last updated Jun 05, 2026 12:09 UTC
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Pre-Surgery exercise boosts strength before knee replacement
Symptom relief CompletedThis study tested a pre-surgery exercise program using blood-flow restriction training in 16 older adults waiting for total knee replacement. The goal was to see if it is safe, well-tolerated, and improves muscle strength and function before surgery. Results will help design larg…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Jun 16, 2026 20:20 UTC
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Robot-Guided brain zaps ease PTSD in just two weeks
Symptom relief CompletedThis study tested whether a quick, two-week course of image-guided, robot-delivered transcranial magnetic stimulation (TMS) could reduce PTSD symptoms in 7 veterans and active-duty service members. Participants received daily TMS sessions targeting the right prefrontal cortex. Ea…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Jun 16, 2026 20:17 UTC
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Could a nasal spray boost PTSD therapy? small study says maybe
Symptom relief CompletedThis early study tested whether adding esketamine (a nasal spray approved for depression) to prolonged exposure therapy could help ease PTSD symptoms. Four adults with PTSD took part. The goal was to see if the combination was safe, acceptable, and worth studying further.
Phase: PHASE1, PHASE2 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Jun 15, 2026 19:06 UTC
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Virtual reality + exercise shows promise for Parkinson's symptoms
Symptom relief CompletedThis small study tested whether combining aerobic exercise with virtual reality can improve walking, balance, and thinking in people with Parkinson's disease. Ten participants completed the program, and researchers measured changes in movement, cognition, and brain activity. The …
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Jun 15, 2026 18:56 UTC
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Nutrition boost may aid hip fracture recovery in seniors
Symptom relief CompletedThis pilot study tested a special nutrition program for older adults (ages 65-89) recovering from hip fracture surgery. The goal was to see if better nutrition could reduce complications, hospital readmissions, and help patients regain strength. 40 participants received dietary g…
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated Jun 08, 2026 13:06 UTC
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Calmer cleanings: Sensory-Friendly dentist eases Kids' dental fears
Symptom relief CompletedThis study tested a specially adapted dental environment for 20 children with sensory processing disorders. The dental office used dim lights, noise-canceling headphones, and gentle tools to reduce anxiety. Researchers measured heart rate, blood pressure, and behavior to see if t…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated May 26, 2026 12:09 UTC
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AI-Powered pregnancy app shows promise in small study
Knowledge-focused CompletedThis study tested a mobile app called JUN that uses artificial intelligence to track symptoms and give timely advice to pregnant women. Researchers wanted to see if using the app helps women feel more confident about managing their health, especially those under criminal justice …
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:52 UTC
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Dexamethasone in bone grafts: a better way to save jawbone after tooth removal?
Knowledge-focused CompletedThis study looked at whether mixing a bone graft with dexamethasone (an anti-inflammatory drug) helps preserve jawbone better than mixing it with saline after a tooth is pulled. 44 adults who needed a tooth removed and planned to get a dental implant took part. Researchers measur…
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:04 UTC
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COVID-19's hidden aftermath: diabetes risk revealed
Knowledge-focused CompletedThis study investigated whether people hospitalized with severe COVID-19 are more likely to develop diabetes later on. Researchers followed 23 participants who had no diabetes before their infection, measuring their blood sugar levels over time. The goal was to understand how COV…
Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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Ketones may change how the heart works in diabetes patients
Knowledge-focused CompletedThis study looked at how raising ketone levels in the blood affects heart function and sugar use in 41 adults with type 2 diabetes and mild-to-moderate heart failure. Researchers used MRI and PET scans to measure heart pumping and energy use. The goal was to understand the body's…
Phase: PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:55 UTC
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HIV and weed: 28-Day break shows surprising health effects
Knowledge-focused CompletedThis study looked at whether people with HIV who regularly use cannabis can stop for 28 days and what happens to their mood, pain, sleep, and HIV levels. 25 participants were given money rewards for staying cannabis-free. The goal was to see if this break is possible and if it re…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 11, 2026 11:57 UTC
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Which bone graft works best? new study compares fibers vs particles for stronger jawbone
Knowledge-focused CompletedThis study tested two forms of donated bone graft material (fibers vs particles) in 26 people needing sinus lifts for dental implants. Researchers measured how much new bone formed six months after surgery. The goal was to see which graft type leads to stronger jawbone for implan…
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:04 UTC
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New study aims to predict hidden aggressive prostate cancer
Knowledge-focused CompletedThis study gathered information and samples from 382 men with low-grade prostate cancer to create a tool that can better predict if the cancer is actually more aggressive than it appears. The goal is to help doctors and patients make more informed decisions about treatment. Parti…
Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated May 28, 2026 12:03 UTC