Sixth Affiliated Hospital, Sun Yat-sen University

This study directly compares two newer medications, ustekinumab (an injection) and upadacitinib (a pill), for people with Crohn's disease that hasn't responded well to standard treatments. It will enroll 454 adults who previously failed on common biologic drugs like infliximab or…

This study is testing if adding a specific diet to standard Crohn's disease medication leads to better healing of the gut lining. It will involve 185 adults in China who are starting a new type of drug treatment. Participants will be randomly assigned to receive either the medica…

This study is testing how well and how safely a drug called an IL-23 monoclonal antibody works for people with moderate to severe Crohn's disease or ulcerative colitis. It will follow 200 adult patients for about a year, checking their symptoms, doing scans and scopes, and collec…

This study is testing a new treatment for infertility caused by severe scarring inside the uterus (intrauterine adhesions). Researchers will infuse stem cells from a patient's own bone marrow directly into the artery supplying the uterus to see if this helps repair the uterine li…

This study is testing if adding a citrus flavonoid tablet (Aimailang) to standard chemotherapy (mFOLFOX6) works better for shrinking rectal tumors before surgery. It will involve 236 patients with locally advanced rectal cancer who have high levels of a specific protein called YW…

This study aims to find the best schedule for a breathing technique used during surgery to keep patients' lungs properly inflated. It will test different time intervals for the technique on 52 older adults having abdominal surgery. The goal is to reduce lung collapse during surge…

This study aims to find out if using a lower concentration of oxygen (30%) just before removing a patient's breathing tube after abdominal surgery leads to fewer breathing problems compared to the standard practice of using pure oxygen (100%). It will involve 590 adults undergoin…

This study aims to see how well a newer class of drugs, called IL-23 inhibitors, works for Chinese adults with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. It will follow 178 patients in real-world clinics for one year to check if the drugs …

This study is testing a new camera technology called Red Dichromatic Imaging (RDI) during a procedure to remove early-stage cancers in the stomach, esophagus, or colon. The goal is to see if RDI helps doctors see blood vessels and control bleeding better than the standard white-l…

This study is testing a smartphone app that uses artificial intelligence to help people prepare for colonoscopies. Patients will use the app at home to take photos of their stool after taking the prep solution; the AI will assess if their bowel is clean enough. If the app predict…

This study is testing if a daily Bergmann enema can prevent painful rectal injury in people receiving short-course radiation for rectal cancer. The goal is to see if this simple treatment can reduce the rate of moderate-to-severe injury from 80% down to 50%. About 40 patients wil…