Which anesthesia is safer for septic lungs? new trial aims to find out
NCT ID NCT07601256
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will compare two common anesthesia methods—inhaled gas versus intravenous drugs—to see which one causes less lung injury after major surgery in patients with sepsis. About 480 adults with sepsis who need surgery will be randomly assigned to one of the two groups. Researchers will track how many days patients need a ventilator and monitor their recovery for up to 90 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sevoflurane (inhalation anesthesia) and ciprofol (intravenous anesthesia), both with remifentanil
- What this could lead to
- If it works, this could show that one type of anesthesia is better at protecting the lungs of sepsis patients during surgery, potentially improving recovery.
- What could go wrong
- This is an early-stage trial (Phase NA) testing a comparison of existing drugs, not a new treatment. The results may show no difference or may not apply to all sepsis patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Sixth Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, 510655, China
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