Can a simple diet boost Crohn's treatment? new trial aims to find out

NCT ID NCT07344428

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a special diet (the Crohn's Disease Exclusion Diet) to standard biologic drugs can improve gut healing in adults with active Crohn's disease. About 185 participants in China will be randomly assigned to receive either the diet plus biologics or biologics alone. The main goal is to see if more patients achieve complete healing of the gut lining at 14 weeks with the combined approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Crohn's Disease Exclusion Diet (CDED) combined with anti-TNF-α biologics (infliximab or adalimumab)

What this could lead to

If it works, this could point toward a more effective way to heal the gut lining in Crohn's disease, potentially reducing the need for surgery or stronger medications.

What could go wrong

This is a small, early-stage trial in one country, so results may not apply to everyone. The diet is strict and hard to follow, and the improvement in healing may be modest or not statistically significant.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sixth afflicated of Sun-yat sen university

    Guangzhou, Guangdong, 510655, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••