Sixth Affiliated Hospital, Sun Yat-sen University
Clinical trials sponsored by Sixth Affiliated Hospital, Sun Yat-sen University, explained in plain language.
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Could a common pill boost biologic therapy for ulcerative colitis?
Disease control CompletedThis study looked at whether adding mesalazine (a standard anti-inflammatory drug) to biologic treatments helps more people with moderate to severe ulcerative colitis reach endoscopic remission (healing of the gut lining). 438 adults took part. The goal was to see if the combinat…
Phase: PHASE4 • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 17, 2026 00:30 UTC
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New imaging technique reveals how well Crohn's drug works
Disease control CompletedThis study looked at 150 adults with Crohn's disease who were treated with ustekinumab, a biologic drug. Researchers used special imaging scans to measure inflammation deep in the gut wall and checked if this helped predict how well the drug worked over 12 months. The goal was to…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New model predicts surgery risk for Crohn's patients
Knowledge-focused CompletedThis study looked at 300 people with Crohn's disease to see if medical imaging could help predict who would need surgery within the first year after diagnosis. The researchers created a computer model using radiomics—a way to analyze images for hidden patterns. The goal is to hel…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 17, 2026 00:44 UTC
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Colon cancer study reveals key link between DNA repair and lymph node spread
Knowledge-focused CompletedThis study looked at 1,471 people with colon cancer to see how their tumor's DNA repair system (called MMR status) affects where the cancer spreads and how long they live. Researchers compared two groups: those with normal repair (pMMR) and those with faulty repair (dMMR). The go…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 17, 2026 00:42 UTC
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Small change in wrist stick location could make blood pressure monitoring more reliable
Knowledge-focused CompletedThis study looked at whether placing an arterial line 1.5-2.5 cm higher on the wrist (instead of right at the joint) reduces problems like kinking or blockage. Researchers monitored 486 surgery patients to see if the new spot made blood pressure readings more stable. The goal was…
Phase: NA • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 17, 2026 00:29 UTC
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New study reveals key risk factors for rectal Cancer's return after surgery
Knowledge-focused CompletedThis study looked at 298 patients who had surgery for rectal cancer that came back in the same area. The goal was to see how long they stayed cancer-free and what factors made the cancer more likely to return again. Researchers used medical records and imaging to track outcomes a…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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New biologics show promise for Crohn's in chinese patients
Knowledge-focused CompletedThis study looked at how well two newer biologic drugs, Ustekinumab and Vedolizumab, work for people with Crohn's disease in China. Researchers tracked 50 patients to see if the drugs helped heal the gut and reduce symptoms, and also checked for side effects. The goal was to gath…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Hidden fistulas found early may change Crohn's prognosis
Knowledge-focused CompletedThis study reviewed medical records of 669 Crohn's disease patients to see if finding anal fistulas early—before symptoms appear—leads to better outcomes. Researchers compared patients whose fistulas were found by routine MRI (no symptoms) to those who already had symptoms. The g…
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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New study aims to spot which newborns with gut disease will get worse
Knowledge-focused CompletedThis study looked back at the medical records of 400 newborns with a serious gut disease called necrotizing enterocolitis (NEC). The goal was to see if combining blood test results, organ function scores, and other clinical signs could better predict which babies would develop a …
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC