Colon cancer clues: DNA repair status may guide surgery decisions

NCT ID NCT06798857

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This completed study looked at 1,471 colon cancer patients to see how their tumor's DNA repair status (pMMR vs dMMR) relates to lymph node spread and survival. Researchers hope to identify patients who might not need extensive lymph node removal. The study is observational and does not test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could help doctors decide which colon cancer patients can safely avoid extensive lymph node removal during surgery.
What could go wrong
This is an observational analysis of past data, not a treatment trial. The findings may not change practice without further prospective studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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