Colon cancer clues: DNA repair status may guide surgery decisions

NCT ID NCT06798857

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 24 times

Summary

This completed study looked at 1,471 colon cancer patients to see how their tumor's DNA repair status (pMMR vs dMMR) relates to lymph node spread and survival. Researchers hope to identify patients who might not need extensive lymph node removal. The study is observational and does not test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors decide which colon cancer patients can safely avoid extensive lymph node removal during surgery.

What could go wrong

This is an observational analysis of past data, not a treatment trial. The findings may not change practice without further prospective studies.

Conditions

The condition(s) this trial relates to.

colon adenocarcinoma colon carcinoma colonic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.