Second Affiliated Hospital, School Of Medicine, Zhejiang University

This early-phase study tests a personalized vaccine made from a patient's own tumor mutations. It is given to people with esophageal cancer who have already completed surgery and standard treatments. The goal is to see if the vaccine is safe and can help prevent the cancer from c…

This study looks at whether giving the drug serplulimab together with chemotherapy before surgery can help people with a certain type of lung cancer (non-small cell lung cancer). The goal is to shrink tumors and make surgery more effective, possibly reducing the chance of cancer …

This study is testing two new drug combinations for people with a specific genetic mutation (KRAS G12C) in advanced colorectal cancer that has spread. One group gets the drugs as their first treatment, and another group gets them after standard treatment stops working. The goal i…

This study tests whether adding the drug serplulimab to standard chemotherapy before surgery can help people with esophageal cancer. The goal is to see if this combination can shrink tumors more effectively and lower the chance of cancer coming back after surgery. About 48 adults…

This study looks at whether giving antibiotics before an endoscopic procedure is necessary for cirrhosis patients who have had variceal bleeding before. The goal is to see if skipping antibiotics is just as safe and effective. About 226 adults with cirrhosis are taking part.

This study tests a new drug (orelabrutinib) combined with either low-dose radiation or another drug (rituximab) for a rare type of eye lymphoma called ocular adnexal MALT lymphoma. The goal is to see how well the treatment shrinks or eliminates the cancer. The trial includes 39 a…

This study tests a safe, non-invasive treatment called distant ischemic adaptation for people who have had a stroke or have small vessel brain disease. The treatment involves briefly inflating a blood pressure cuff on the arm to trigger the body's natural protection. Researchers …

This study tests a new way to remove kidney stones (2-4 cm) called VISOR, comparing it to standard surgery (PCNL). About 170 adults will be randomly assigned to one of the two procedures. Researchers will check how many people are stone-free right after surgery and one month late…

This study looks at whether adding a special shockwave therapy (intravascular lithotripsy) to the usual artery-clearing procedure helps people with moderate to severe calcium buildup in their heart arteries. About 1,096 adults with coronary artery disease will be split into two g…

This study tests a new approach for treating deep brain bleeds. It combines a computer-guided, minimally invasive surgery to drain the clot with a clot-dissolving medicine. The goal is to see if this helps people recover better and regain independence compared to standard care. T…

This early-stage study tests whether beta-sitosterol, a safe plant compound found in traditional Chinese medicine, can help people recover from a severe type of stroke called subarachnoid hemorrhage. About 40 adults who had a bleeding stroke will receive beta-sitosterol within 48…

This study tests whether icaritin soft capsules can help prevent liver cancer from coming back after surgery in patients at high risk of recurrence. Twenty adults who had their liver cancer completely removed will take the capsules and be monitored with scans every three months. …

This phase 3 trial tests whether adding the immunotherapy drug sintilimab to standard chemotherapy and bevacizumab helps people with a specific type of advanced colorectal cancer (RAS-mutant, MSS) live longer without their cancer growing. About 446 adults who have not had prior t…

This study tests whether platelet-rich plasma (PRP) or corticosteroid injections work better for different types of shoulder tendon problems after surgery. About 387 adults with rotator cuff tears will receive one of three treatments. The goal is to find the best way to ease pain…

This study tested a small electrical nerve stimulation device (TENS) to see if it can reduce migraine pain and related symptoms like nausea and light sensitivity. About 200 adults with migraines took part in a double-blind trial where some used the real device and others a fake o…

This study looks at brain tissue from 10 people with temporal lobe epilepsy and hippocampal sclerosis who are having surgery. Researchers will analyze gene activity in the removed tissue to find clues about what causes the disease and how it progresses. The goal is to better unde…

This study tests a new adaptive fluidics system that automatically adjusts fluid pressure during lens surgery to keep the eye stable and reduce risks. About 320 adults with lens diseases will be enrolled to see if this technology improves safety and surgical outcomes compared to …

This study looks at how PET/CT scans can be used with artificial intelligence to better understand non-small cell lung cancer. Researchers will analyze scans from 500 patients to see if they can predict cancer stage, type, gene changes, and patient outcomes. The goal is to help d…

This study looks at whether a special cholesterol test (VAP) can help predict if arteries will narrow again after a stent procedure. Researchers will study 3,600 adults who have had stents placed, using blood samples already collected during routine care. The goal is to see if ce…