Shockwave therapy may crack tough heart artery plaque
NCT ID NCT07340294
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using a shockwave device (intravascular lithotripsy) along with standard artery preparation can improve outcomes for people with moderate to severe coronary artery calcification. About 1,096 participants will be split into two groups: one gets standard prep alone, the other gets standard prep plus the shockwave. Researchers will track heart-related events over 24 months to see if the combo approach reduces the need for repeat procedures or prevents heart attacks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Intravascular lithotripsy (shockwave device)
What this could lead to
If successful, this could offer a better way to treat hardened arteries in the heart, reducing the risk of heart attacks or repeat procedures.
What could go wrong
This is an early-stage study with no phase designation, so results are uncertain. The device may not improve outcomes over standard care, and there are risks like vessel injury or complications from the procedure.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CORONARY ARTERY CALCIFICATION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Second Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
-
The First Affiliated Hospital of Nanchang University (FAHNU)
Nanchang, Jiangxi, China
-
The People's Hospital of Liaoning Province
Shenyang, Liaoning, China
-
Tianjin Fourth Central Hospital
Tianjin, China