Scoring balloon aims to crack tough heart plaques for better stent fit
NCT ID NCT07650578
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether a specialized scoring balloon, called Naviscore, can better prepare calcified coronary arteries before placing a drug-eluting stent. Hardened plaques often prevent stents from expanding fully, raising risks of re-narrowing or clots. About 200 adults with moderate to severe calcium buildup in their heart arteries will be randomly assigned to receive either the Naviscore balloon or a standard non-compliant balloon. The main goal is to see if the Naviscore leads to a larger final stent area, measured by ultrasound, at the site of the heaviest calcium.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Naviscore scoring balloon catheter
What this could lead to
If successful, this device could improve stent placement in patients with hardened arteries, reducing the risk of re-narrowing or clots.
What could go wrong
This is a mid-stage trial with 200 participants, so results may not apply to all patients. The device may not outperform standard balloons, and risks include vessel injury or no benefit.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHR de la Citadelle
Liège, 4000, Belgium
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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CHU - HELORA site Kennedy
Mons, Hainaut, 7000, Belgium
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Contact
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Centro Hospitalar de Vila Nova de Gaia/Espinho
Vila Nova de Gaia, 4430-999, Portugal
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Hospital Clínico Universitario de Valladolid
Valladolid, 47003, Spain
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Contact
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Hospital La Fe
Valencia, 46026, Spain
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Hospital Puerta Del Mar
Cadiz, 11009, Spain
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Hospital San Pedro de Alcantara
Cáceres, 10003, Spain
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Hospital Universitari de Bellvitge
Barcelona, 08901-08908, Spain
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Hospital de Sant Pau
Barcelona, 08025, Spain
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Humani CHU Charleroi - Chimay
Lodelinsart, 6042, Belgium
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Hôpital Erasme - Cliniques universitaires de Bruxelles
Brussels, 1070, Belgium
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Hôpital Vivalia
Libramont, 6800, Belgium
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INCCI Haerz Zenter
Luxembourg, 1210, Luxembourg
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Contact
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Imelda
Bonheiden, 2820, Belgium