Regeneron Pharmaceuticals

This early-stage study tested the safety and initial effectiveness of a new drug called odronextamab in 200 adults with advanced non-Hodgkin lymphoma or chronic lymphocytic leukemia. The drug is designed to attach to cancer cells and the immune system to help the body fight the c…

This study tested whether giving an immunotherapy drug called cemiplimab to patients before surgery could help shrink their advanced skin cancer tumors. The goal was to see if this approach led to better surgical outcomes and longer survival. The trial involved 79 patients with a…

This study tested whether the drug dupilumab could safely reduce inflammation and improve symptoms in children with eosinophilic esophagitis (EoE), a chronic condition that makes swallowing difficult. Over 100 children participated, receiving either the drug or a placebo for 16 w…

This study observed how well the immunotherapy drug cemiplimab worked for patients with advanced forms of two common skin cancers (squamous cell and basal cell carcinoma) in real-world clinics, not just in a controlled trial. It tracked 287 patients to see how their tumors respon…

This large, completed Phase 3 trial tested whether a new immunotherapy drug (cemiplimab) works better than standard platinum-based chemotherapy as the first treatment for patients with advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors have high levels of a ma…

This study tested an experimental drug called cemiplimab, injected directly into skin cancer tumors before surgery. The main goal was to see if this approach was safe and how well patients tolerated it. Researchers also looked at whether the injections could shrink the tumors.

This was an early-stage study to check the safety of an experimental drug called ALN-APOC3 in 32 adults with dyslipidemia, which means they have unhealthy levels of fats like cholesterol and triglycerides in their blood. The main goal was to see if the drug was safe and how the b…

This study tested whether combining an immunotherapy drug (cemiplimab) with a vaccine (ISA101b) could help control advanced cervical cancer that had worsened after standard chemotherapy. It involved 113 adult patients whose cancer was caused by the HPV16 virus and had spread or r…

This study tested whether an injectable drug called dupilumab is effective and safe for treating bullous pemphigoid, a serious autoimmune disease that causes severe blistering and itching, mostly in older adults. The trial involved 106 participants and compared dupilumab against …

This study tested an experimental drug called REGN4461 in people with generalized lipodystrophy, a rare disorder where the body cannot store fat properly. The main goal was to see if the drug could help lower high blood sugar and high triglyceride (fat) levels in the blood. Sixte…

This study aimed to gather more information on the safety and effectiveness of the drug dupilumab specifically for people with skin of color who have moderate-to-severe eczema (atopic dermatitis). It involved 124 adolescent and adult participants and measured how well the drug im…

This study tested an experimental drug, REGN7508, to see if it could safely prevent dangerous blood clots (venous thromboembolism) in adults after elective knee replacement surgery. It involved 179 participants and directly compared the new drug to an existing standard treatment.…

This early-stage study tested the safety of a combination of two lab-made antibodies (casirivimab+imdevimab) against COVID-19. It involved 45 healthy or medically stable adult volunteers who received the antibodies either as an injection under the skin or through an IV drip. The …

This study tested whether two experimental drugs, REGN1908 and REGN1909, could safely reduce the itchy, red, and watery eyes people with cat allergies experience. The trial involved 64 participants with confirmed cat allergies who did not live with cats. They were randomly assign…

This study tested whether two experimental drugs, given together as eye drops, could safely reduce the signs and symptoms of eye allergies caused by birch pollen. In this Phase 3 trial, 54 adults with a confirmed birch pollen allergy received either the real treatment or a placeb…

This study aimed to understand the safety of using the medication dupilumab during pregnancy. Researchers followed 581 pregnant women in North America, comparing those who took the drug for eczema or asthma to those who did not. The main goal was to check for any effects on the b…

This was the first study to give a new experimental drug called REGN9533 to people. The main goal was to check if the drug is safe and to find a good dose in 72 healthy volunteers. This early research is a necessary first step before testing the drug in people who have blood clot…

This study looked back at the medical records of 550,000 patients who received aflibercept (Eylea) injections for common eye diseases like macular degeneration and diabetic eye swelling. The goal was to measure how often a serious eye inflammation called retinal vasculitis occurr…

This study aimed to understand if giving a COVID-19 antibody treatment (casirivimab+imdevimab) affects the body's immune response to the Moderna mRNA-1273 vaccine. Researchers enrolled 295 healthy adults to receive the vaccine at different times after the antibody treatment. The …

This study looked back at health insurance records for nearly 300,000 people who received aflibercept eye injections. The goal was to understand how often a serious eye inflammation called retinal vasculitis happens after these injections. Researchers analyzed data from 2017 to 2…