Regeneron Pharmaceuticals

This study looked at whether giving a COVID-19 antibody treatment (casirivimab+imdevimab) along with the Moderna vaccine changes how well the vaccine works. About 295 healthy adults took part. Researchers wanted to see if the timing between the antibody treatment and the vaccine …

This early-phase study tested an experimental immunotherapy drug, cemiplimab, given as injections directly into skin tumors before surgery. The goal was to see if the drug is safe and how well it shrinks or eliminates the cancer. The study included 97 people with two common types…

This study looked at how well the drug dupilumab works for people with skin of color who have moderate-to-severe eczema (atopic dermatitis). Eczema causes itchy, dry, cracked skin. The study included 124 adolescents and adults and measured skin improvement after 24 weeks. The goa…

This study tested a combination of an immunotherapy drug (cemiplimab) and a vaccine (ISA101b) in 113 adults with advanced HPV16-positive cervical cancer that had worsened after standard chemotherapy. The goal was to see if the combination could shrink tumors or slow the disease. …

This study tested a drug called dupilumab in 102 children with active eosinophilic esophagitis (EoE), a condition where the esophagus becomes inflamed, making swallowing painful. The goal was to see if dupilumab could reduce inflammation better than a placebo after 16 weeks. Rese…

This early-stage study tested a new drug called odronextamab (REGN1979) in 200 people with B-cell blood cancers like non-Hodgkin lymphoma and chronic lymphocytic leukemia that had stopped responding to prior treatments. The goal was to check the drug's safety and find the right d…

This study tested a new immunotherapy drug, cemiplimab, against standard chemotherapy in 712 people with advanced non-small cell lung cancer that has a specific marker (PD-L1). The goal was to see if cemiplimab helps people live longer or keeps the cancer from growing longer than…

This early-stage study tested an experimental drug called ALN-APOC3 in 32 adults with dyslipidemia (abnormal blood fat levels). The main goal was to check safety and side effects, and to see how the drug changes fat levels in the blood. Participants were otherwise healthy and eit…

This study tested whether dupilumab, a drug that calms the immune system, can safely treat bullous pemphigoid—a painful blistering skin disease that mostly affects people over 60. About 106 adults took part. The goal was to see if dupilumab could help patients stop taking steroid…

This early-phase study tested the safety of a combination of two antibodies (casirivimab and imdevimab) given as a shot or through an IV in 45 healthy adults or those with stable chronic conditions. The goal was to see if the treatment is safe and how the body processes it. No di…

This study tested a new drug called REGN4461 in 16 people with generalized lipodystrophy, a rare condition where the body lacks fat tissue, leading to severe metabolic problems like high blood sugar and high triglycerides. The drug aims to mimic a natural hormone (leptin) to impr…

This large Phase 3 study tested adding the immunotherapy drug cemiplimab to standard chemotherapy for people with advanced non-small cell lung cancer. About 789 participants received either the combination or chemo alone. The goal was to see if the combo helped people live longer…

This study tested a new drug called REGN5459 in 43 people with multiple myeloma that had returned or stopped responding to other treatments. The drug is a bispecific antibody designed to help the immune system attack cancer cells. The main goals were to check safety and see if th…

This study tested the drug cemiplimab given before surgery for people with stage II to IV skin cancer (cutaneous squamous cell carcinoma). The main goal was to see if the drug could make the cancer disappear completely by the time of surgery. 79 participants received cemiplimab b…

This study followed 287 people with advanced skin cancers (squamous cell or basal cell) who were treated with the drug cemiplimab in everyday medical practice. Researchers tracked how well the drug shrank tumors, how long benefits lasted, and any side effects. The goal was to see…

This study tested two experimental drugs (REGN9933 and REGN7508) to see if they can prevent blood clots in adults who need a PICC line (a thin tube placed in a vein). The study involved 195 participants and compared the drugs to a placebo. Researchers monitored for clots, side ef…

This study tested an experimental drug called REGN7508 in 179 adults having knee replacement surgery. The goal was to see if it could prevent blood clots in the legs or lungs. Researchers compared the drug to standard care and monitored for side effects and how the drug behaved i…

This study tested two experimental drugs, REGN5713 and REGN5715, given together to reduce eye allergy symptoms caused by birch pollen. 54 adults with a history of moderate to severe birch pollen allergy received either the drug or a placebo. The main goal was to see if the drug c…

This study tested two experimental drugs, REGN1908 and REGN1909, given together to reduce eye allergy symptoms caused by cats. 64 people with moderate to severe cat allergy took part. The goal was to see if the drug is safe and effective at lowering eye itch and redness compared …

This study looked at the safety of using dupilumab during pregnancy in women with atopic dermatitis or asthma. Researchers compared pregnancy and infant outcomes between women who took dupilumab and those who did not. The goal was to see if the drug increased the risk of birth de…

This study looked at nearly 290,000 people in the US who received aflibercept eye injections to treat various retinal diseases. The goal was to find out how often retinal vasculitis (a type of eye inflammation) occurs after these injections. Researchers used a large insurance dat…

This early-stage study tested a single dose of REGN9533 in 72 healthy adults to see if it is safe and how the body handles it. Researchers measured side effects, drug levels in the blood, and whether the body made antibodies against the drug. The goal is to gather safety data bef…

This study looked at how often retinal vasculitis (a rare eye inflammation) occurs in people receiving Eylea injections for eye diseases. Researchers reviewed medical records of over 550,000 patients in the US to count cases and confirm them. The goal was to better understand the…