New drug shows promise for rare fat disorder

NCT ID NCT04159415

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called REGN4461 in 16 people with generalized lipodystrophy, a rare condition where the body can't store fat properly, leading to severe metabolic problems. The drug aims to improve blood sugar and triglyceride levels. Participants received either the drug or a placebo for 8 weeks to see if it helps control these issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GENERALIZED LIPODYSTROPHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

generalized lipodystrophy Lipodystrophy, Congenital Generalized

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Regeneron Research Site

    Bethesda, Maryland, 20892, United States

  • Regeneron Research Site

    Ann Arbor, Michigan, 48105, United States

  • Regeneron Research Site

    Dallas, Texas, 75390, United States

  • Regeneron Research Site

    Piura, 2665, Peru

  • Regeneron Research Site

    Moscow, 117036, Russia

  • Regeneron Research Site

    Ankara, 06230, Turkey (Türkiye)

  • Regeneron Research Site

    Diyarbakır, 21808, Turkey (Türkiye)

  • Regeneron Research Site

    Izmir, 35100, Turkey (Türkiye)