Immunotherapy cocktail extends life in advanced lung cancer trial

NCT ID NCT03409614

Completed Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Apr 30, 2026 · Last updated May 10, 2026 · Updated 2 times

Summary

This large Phase 3 study tested adding the immunotherapy drug cemiplimab to standard chemotherapy for people with advanced non-small cell lung cancer. About 789 participants received either the combination or chemo alone. The goal was to see if the combo helped people live longer and slowed cancer growth. Results showed improved survival, supporting this as a new treatment option.

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Contacts and locations

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Locations

Regeneron Research Site

Rancho Mirage, California, 92270, United States
Regeneron Research Site

Riverside, California, 92506, United States
Regeneron Research Site

Whittier, California, 90603, United States
Regeneron Research Site

Orange City, Florida, 32763, United States
Regeneron Research Site

St. Petersburg, Florida, 33709, United States
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Wichita, Kansas, 67214, United States
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Bethesda, Maryland, 20817, United States
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Farmington, New Mexico, 87401, United States
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Gettysburg, Pennsylvania, 17325, United States
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Vienna, 1130, Austria
Regeneron Research Site

Baoding, 071105, China
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Changsha, 410013, China
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Guangzhou, 510080, China
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Hangzhou, 310002, China
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Hangzhou, 310003, China
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Hangzhou, 310009, China
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Hangzhou, 310013, China
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Jinan, 250013, China
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Linyi, 276001, China
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Nanjing, 210003, China
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Shanghai, 200040, China
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Shanghai, 200433, China
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Shenyang, 110042, China
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Xiangyang, 441021, China
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Zhengzhou, 450003, China
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Zhengzhou, 450008, China
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Bayonne, 64100, France
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Créteil, 94010, France
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Le Mans, 72000, France
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Lille, 59037, France
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Lyon, 69310, France
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Mont-de-Marsan, 40024, France
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Saint-Herblain, 44805, France
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Saint-Mandé, 94160, France
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Strasbourg, 67091, France
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Batumi, 6000, Georgia
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Tbilisi, 0112, Georgia
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Tbilisi, 0144, Georgia
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Tbilisi, 0186, Georgia
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Thessaloniki, Macedonia, 54645, Greece
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Athens, 11527, Greece
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Kifissia, 14564, Greece
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Larissa, 41334, Greece
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Pylaia, 57001, Greece
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Thessaloniki, 54007, Greece
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Dublin, 9, Ireland
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Limerick, V94F858, Ireland
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Cremona, 26100, Italy
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Meldola, 47014, Italy
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Milan, 20162, Italy
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Monserrato, 09042, Italy
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Piacenza, 29121, Italy
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Saronno, 21047, Italy
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Terni, 05100, Italy
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Treviglio, 24047, Italy
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Klaipėda, LT-92288, Lithuania
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Vilnius, LT-08660, Lithuania
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Kuala Lumpur, Kuala Lumpur, 59100, Malaysia
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George Town, 10350, Malaysia
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Johor Bahru, 81100, Malaysia
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Kota Kinabalu, 88996, Malaysia
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Kuala Lumpur, 56000, Malaysia
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Kuala Lumpur, 59100, Malaysia
Regeneron Research Site

Kuantan, 25100, Malaysia
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Pulau Pinang, 10990, Malaysia
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Tanjung Bungah, 11200, Malaysia
Regeneron Research Site

Gdynia, Pomeranian Voivodeship, 81-519, Poland
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Lodz, 90-302, Poland
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Lublin, 20-093, Poland
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Olsztyn, 10-357, Poland
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Otwock, 05-400, Poland
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Poznan, 60-693, Poland
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Rzeszów, 35-021, Poland
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Torun, 87-100, Poland
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Wodzisław Śląski, 44-300, Poland
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Cluj-Napoca, 400006, Romania
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Cluj-Napoca, 400124, Romania
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Craiova, 200094, Romania
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Craiova, 200347, Romania
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Craiova, 200385, Romania
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Ufa, Republic Bashkortost, 450054, Russia
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Arkhangelsk, 163045, Russia
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Belgorod, 308010, Russia
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Chelyabinsk, 454048, Russia
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Kaluga, 248007, Russia
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Kazan', 420029, Russia
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Kursk, 305016, Russia
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Moscow, 115478, Russia
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Moscow, 121467, Russia
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Moscow Region, 143444, Russia
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Omsk, 644013, Russia
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Pushkin, 196603, Russia
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Pyatigorsk, 357502, Russia
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Saint Petersburg, 191104, Russia
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Saint Petersburg, 197758, Russia
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Saint Petersburg, 198255, Russia
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Samara, 443001, Russia
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Saransk, 430032, Russia
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Sochi, 354057, Russia
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Tomsk, 634028, Russia
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Tomsk, 634050, Russia
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Yekaterinburg, 620036, Russia
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Banka, 92101, Slovakia
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Cheongju-si, 28644, South Korea
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Incheon, 21565, South Korea
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Jeonju, 54907, South Korea
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Seongnam-si, 13496, South Korea
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Seongnam-si, 13620, South Korea
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Seoul, 05368, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Suwon, 16499, South Korea
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Muang, Changwat Chiang Rai, 57000, Thailand
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A. Mueang, Changwat Lampang, 52000, Thailand
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Muang, Changwat Phitsanulok, 65000, Thailand
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Hat Yai, Changwat Songkhla, 90110, Thailand
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Udon Thani, Udonthani, 41330, Thailand
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Muang, 15000, Thailand
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Adana, 01120, Turkey (Türkiye)
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Ankara, 06100, Turkey (Türkiye)
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Istanbul, 34000, Turkey (Türkiye)
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Istanbul, 34093, Turkey (Türkiye)
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Dnipro, 49102, Ukraine
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Kharkiv, 61070, Ukraine
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Kiev, 03022, Ukraine
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Kirovohrad, 25006, Ukraine
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Uzhhorod, 88014, Ukraine
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Vinnytsia, 21029, Ukraine
Regeneron Research Site #1

Tbilisi, 0159, Georgia
Regeneron Research Site #1

Ratchathewi, 10400, Thailand
Regeneron Research Site #2

Tbilisi, 0159, Georgia
Regeneron Research Site #2

Ratchathewi, Bangkok, 10400, Thailand
Regeneron research Site

Beijing, 100050, China

Conditions

Explore the condition pages connected to this study.

NON-SMALL CELL LUNG CANCER NON-SMALL CELL LUNG CANCER