Regeneron Pharmaceuticals

This study tested a single dose of two monoclonal antibodies (casirivimab+imdevimab) given intravenously to children hospitalized with COVID-19. The goal was to measure how the drug behaves in the body and check for side effects. Only 2 children were enrolled before the study was…

This study tested an experimental drug, REGN5093-M114, for people with advanced non-small cell lung cancer that has too much MET protein. The goal was to find a safe dose and see if the drug could shrink tumors, either alone or with another drug called cemiplimab. The study was t…

This study tested a combination of two antibodies (REGN14256 and imdevimab) in adults with mild COVID-19 who were not at high risk for severe illness. The goal was to see if the treatment was safe and could reduce the amount of virus in the body. The study was stopped early, and …

This study tested an experimental drug called REGN5381 in 34 adults whose high blood pressure remained high despite taking one or more standard medications. The goal was to see if the drug could safely lower blood pressure further. The study was stopped early, so results are limi…

This study tested an experimental drug called REGN7257 in 17 people with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. The drug aims to help patients whose disease did not improve or came back after standard immune-suppressing treatmen…

This study tested a single shot of two lab-made antibodies (casirivimab and imdevimab) in children under 12 who are at high risk for severe COVID-19. The goal was to measure how long the antibodies stay in the blood and check for side effects. Only 7 children took part before the…

This early-phase study tested a new treatment called bbT369 for people with a type of blood cancer (B cell non-Hodgkin's lymphoma) that had come back or stopped responding to standard treatments. The therapy uses a patient's own immune cells, which are modified in a lab to better…

This study tested a drug called REGN4461 in 20 people with a rare condition called familial partial lipodystrophy, which causes abnormal fat storage and serious metabolic issues like high triglycerides and blood sugar. The trial was split into two groups based on leptin levels an…

This study tested a single dose of an experimental drug called REGN5381 in 89 people with chronic heart failure whose hearts pump less blood than normal. The goal was to check safety, side effects, and how the drug affects heart stress markers. The study was terminated early, so …

This study tested whether injecting a drug called vidutolimod directly into tumors, combined with an intravenous immunotherapy (cemiplimab), could shrink or control advanced cancers like Merkel cell carcinoma, skin cancer, breast cancer, and lung cancer. The trial enrolled 77 adu…

This study tested a new treatment called BPX-601 for people with advanced prostate cancer that had stopped responding to other therapies. The treatment uses a patient's own immune cells, which are modified in a lab to better recognize and attack cancer cells. The main goals were …

This study tested whether adding an experimental drug (CMP-001) injected directly into tumors to the standard immunotherapy nivolumab works better than nivolumab alone for people with advanced melanoma that cannot be removed by surgery or has spread. The trial was stopped early a…

This study tested whether a combination of two lab-made antibodies (casirivimab and imdevimab) could prevent symptomatic COVID-19 in people with weakened immune systems, such as transplant recipients or those on immunosuppressant drugs. The study was stopped early after enrolling…