Experimental drug for rare bone marrow disease shows early promise, but study halted
NCT ID NCT04409080
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an experimental drug called REGN7257 in 17 people with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. The drug was given to patients whose disease did not get better or came back after standard immune-suppressing treatments. The main goal was to check safety and see if the drug could improve blood cell counts, but the study was stopped early.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Ewha Womans University Medical Centre
Seoul, Seoul Capital Area, 07985, South Korea
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Gachon University Gil Hospital
Incheon, Gyeonggi-do, 21565, South Korea
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Hopital Saint-Louis - APHP
Paris, Île-de-France Region, 75010, France
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King's College Hospital, London
London, SE5 9RS, United Kingdom
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Samsung Medical Center
Seoul, Seoul Capital Area, 06351, South Korea
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Seoul National University Hospital
Seoul, Seoul Capital Area, 03080, South Korea
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St James's University Hospital
Leeds, West Yorkshire, LS97TF, United Kingdom
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The Catholic University of Korea, Seoul St. Marys Hospital
Seoul, Seoul Capital Area, 06591, South Korea
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States