New drug hope for bone marrow failure patients

NCT ID NCT04409080

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 19 times

Summary

This study tested an experimental drug called REGN7257 in 17 people with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. The drug aims to help patients whose disease did not improve or came back after standard immune-suppressing treatments. The study was stopped early, and its main goal was to check safety and see if blood cell counts improve.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • Ewha Womans University Medical Centre

    Seoul, Seoul Capital Area, 07985, South Korea

  • Gachon University Gil Hospital

    Incheon, Gyeonggi-do, 21565, South Korea

  • Hopital Saint-Louis - APHP

    Paris, Île-de-France Region, 75010, France

  • King's College Hospital, London

    London, SE5 9RS, United Kingdom

  • Samsung Medical Center

    Seoul, Seoul Capital Area, 06351, South Korea

  • Seoul National University Hospital

    Seoul, Seoul Capital Area, 03080, South Korea

  • St James's University Hospital

    Leeds, West Yorkshire, LS97TF, United Kingdom

  • The Catholic University of Korea, Seoul St. Marys Hospital

    Seoul, Seoul Capital Area, 06591, South Korea

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.