New stem cell infusion could boost transplant success in rare blood disorder

This early-phase trial tests whether adding specially grown umbilical cord stem cells to a standard bone marrow transplant can improve outcomes for people with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. About 40 participants aged 6 to 60 will receive the stem cell infusion alongside a half-matched donor transplant. The study focuses on safety and whether the approach reduces complications like graft-versus-host disease and improves survival.