Radboud University Medical Center

This study tests whether a smartphone app that coaches older adults to eat more protein can help them maintain muscle mass and strength. Researchers will enroll 140 participants who are open to changing their diet and using an app. The app provides personalized nutritional coachi…

This study tests whether using personalized dosing (based on drug levels in the blood) for the antibiotic teicoplanin works better than standard dosing for treating bacterial infections. About 74 adults in hospital intensive care or other units will take part. The goal is to see …

This phase 3 trial tests whether colchicine, an anti-inflammatory drug, can slow the progression of aortic valve stenosis—a narrowing of the heart's aortic valve that currently has no drug treatment. The study enrolls 150 people with moderate, symptom-free valve disease. Particip…

This study tests a personalized workplace intervention for 124 Dutch workers with Parkinson's disease, cerebellar ataxia, hereditary spastic paraparesis, or slowly progressive neuromuscular/mitochondrial disorders. A trained facilitator helps employees and their managers identify…

This study tests whether a personalized lifestyle program focusing on stress, exercise, nutrition, sleep, and self-management can improve quality of life for people with Parkinson's disease. 256 participants will be randomly assigned to either work on their goals independently or…

This study tests whether mindfulness-based cognitive therapy (MBCT) can reduce psychological distress in people with Parkinson's disease. 174 participants with mild-to-moderate stress symptoms will either receive MBCT or continue usual care. The main goal is to see if MBCT lowers…

This study follows 250 male endurance athletes who were part of an earlier study to see how their heart arteries have changed over time. Researchers will use CT scans and AI to examine plaque buildup and determine if it is stable and harmless or likely to cause heart attacks. The…

This study looks at two treatments for severe depression: electroconvulsive therapy (ECT) and antidepressant medication. Researchers want to see which one works better and is more cost-effective in the long run. The study involves 220 adults in the Netherlands who have not gotten…