Can brain scans predict who will benefit from tremor injections?

NCT ID NCT06411028

First seen Aug 14, 2026 ยท Last updated Aug 14, 2026

Summary

This study looks at why botulinum toxin injections help only some people with arm tremor related to dystonia. Researchers will measure muscle activity, ultrasound, and brain imaging before treatment, then track tremor severity after three rounds of injections. The goal is to find clues that could predict which patients are most likely to benefit, potentially leading to more personalized care.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Botulinum toxin injections
What this could lead to
If successful, this could help doctors predict which patients with dystonic tremor will benefit most from botulinum toxin, leading to more personalized and effective treatment.
What could go wrong
This is an exploratory study with a small number of participants. It may not identify clear predictors, and the results may not apply to all patients. Botulinum toxin can cause muscle weakness or other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dystonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Canisius-Wilhelmina Ziekenhuis

    Nijmegen, Gelderland, 6532 SZ, Netherlands

  • Donders Centre for Cognitive Neuroimaging

    Nijmegen, Gelderland, 6525 EN, Netherlands

  • Radboud University Medical Center

    Nijmegen, Gelderland, 6525 GA, Netherlands