Can brain scans predict who will benefit from tremor injections?
NCT ID NCT06411028
First seen Aug 14, 2026 ยท Last updated Aug 14, 2026
Summary
This study looks at why botulinum toxin injections help only some people with arm tremor related to dystonia. Researchers will measure muscle activity, ultrasound, and brain imaging before treatment, then track tremor severity after three rounds of injections. The goal is to find clues that could predict which patients are most likely to benefit, potentially leading to more personalized care.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Botulinum toxin injections
- What this could lead to
- If successful, this could help doctors predict which patients with dystonic tremor will benefit most from botulinum toxin, leading to more personalized and effective treatment.
- What could go wrong
- This is an exploratory study with a small number of participants. It may not identify clear predictors, and the results may not apply to all patients. Botulinum toxin can cause muscle weakness or other side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Canisius-Wilhelmina Ziekenhuis
Nijmegen, Gelderland, 6532 SZ, Netherlands
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Donders Centre for Cognitive Neuroimaging
Nijmegen, Gelderland, 6525 EN, Netherlands
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Radboud University Medical Center
Nijmegen, Gelderland, 6525 GA, Netherlands