Peking University First Hospital

This phase 1 trial tested a new treatment called urinary microbiota transplantation (UMT) for people with cystitis glandularis, a chronic bladder condition often linked to pelvic lipomatosis. The treatment involves placing processed donor urine bacteria into the bladder. After on…

Heart failure patients often struggle after leaving the hospital, leading to high readmission rates. This study tested a nurse-led smartphone app that provides medication reminders, symptom tracking, and team support. Half of the 104 participants used the app plus standard care, …

This study looked at 70 people with psoriatic arthritis to compare two drug types: upadacitinib and IL-17 inhibitors. Researchers tracked joint and skin symptoms over 24 weeks in routine care. The goal is to see which works better in real life, helping doctors personalize treatme…

This study looked at whether adding dexmedetomidine to standard morphine pain relief after cancer surgery helps elderly patients (65-90 years) live longer. 1,500 participants were randomly assigned to receive either morphine alone or morphine plus dexmedetomidine for three days a…

This phase 2 trial tested a drug called eculizumab in 16 people with anti-GBM disease, a severe autoimmune condition that often leads to kidney failure. The drug blocks a part of the immune system believed to cause kidney damage. Researchers measured how many patients avoided dia…

This study tested whether an artificial intelligence (AI) system could help find prostate cancer on MRI scans. 365 men who needed a prostate biopsy had their MRI images reviewed by both the AI and by senior radiologists. Doctors then performed targeted biopsies on any suspicious …

This study tests whether combining two sedatives, dexmedetomidine and esketamine, can lower the chance of delirium (sudden confusion) in older patients (60+) after surgery in the ICU. Delirium is common and can lead to worse outcomes. The trial will involve 100 participants and t…

This study compared two painkillers, oliceridine and morphine, in 252 adults undergoing laparoscopic colorectal surgery. The goal was to see if oliceridine causes less nausea and vomiting after surgery. Patients used a pump to control their pain medicine for up to 3 days after th…

This study compared two painkillers, nalbuphine and morphine, given through a patient-controlled pump to women recovering from laparoscopic myomectomy (surgery to remove uterine fibroids). The goal was to see which drug provides better pain relief and causes fewer side effects. E…

This study tested a new epidural pain relief combination (dexmedetomidine, esketamine, and ropivacaine) against the standard mix (sufentanil and ropivacaine) in 300 women during labor. The goal was to see if the new combo works as well for pain and is safer for newborns. It's a p…

This study looked at whether adding dexmedetomidine to standard morphine pain relief after cancer surgery could lower the chance of delirium (sudden confusion) in patients aged 65 and older. A total of 1500 participants were randomly assigned to receive either morphine alone or m…

This study tested whether giving a combination of two sedative drugs (dexmedetomidine and esketamine) at night can improve sleep quality for ICU patients who need a breathing tube or high-flow oxygen mask. The trial involved 174 adults aged 50 and older after surgery. Researchers…

This study aims to create and test a new mathematical formula that estimates how much sodium (salt) people on peritoneal dialysis consume. The researchers will enroll 30 adults who have been on peritoneal dialysis for at least three months and have no remaining kidney function. I…

This early-stage study tested a new drug called Vitalangio1 in 627 healthy adults aged 18–55 to see if it is safe and how the body processes it. Participants took either the drug or a placebo, and some took it with or without food to see how that affects absorption. The study doe…

This study tested whether a series of five one-minute educational videos, shared through community WeChat groups, could improve what people know and do about secondary hypertension. Over 1,000 adults from eight communities in suburban Beijing took part. Researchers measured chang…

This study followed 221 overweight or obese women and their children for 8 to 10 years after a previous trial where some women exercised during pregnancy. Researchers want to see if exercise during pregnancy improves metabolic health, like blood sugar and body weight, in mothers …

This study created a new imaging-based grading system to help doctors predict how complex and risky surgery will be for patients with rare adrenal and nerve tumors called PPGL. Researchers used 3D scans from 500 patients to develop the system, aiming to improve surgical planning …

This study looked at 121 patients who had surgery for Cushing's syndrome (a condition where the body makes too much cortisol). After removing the diseased adrenal gland, patients often need steroid pills while the remaining gland wakes up. Researchers found that the size of the h…