Peking University First Hospital

This study looked at whether adding dexmedetomidine to standard morphine pain relief after cancer surgery helps elderly patients (65-90 years) live longer. 1,500 participants were randomly assigned to receive either morphine alone or morphine plus dexmedetomidine for three days a…

This early-stage trial tests a single injection of RB001, a gene therapy, directly into the fluid around the brain of children with Phelan-McDermid syndrome caused by SHANK3 gene changes. The study includes up to 8 children aged 3 to 17 and primarily checks whether the treatment …

This study follows children with Phelan-McDermid syndrome (a rare genetic disorder causing developmental delays) who received a single dose of RB001 gene therapy injected into the brain. Researchers will monitor them for up to 5 years to see if the treatment is safe and whether i…

This study tests a drug called nimotuzumab combined with radiation and chemotherapy for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combination can better control the tumor for at least a year. The trial will enroll 30 part…

This study tests a flexible scope with a vacuum attachment to remove large kidney stones (2-3 cm). The goal is to see if it clears stones better and lowers risks compared to standard methods. About 115 adults with normal kidney anatomy will take part.

This study tests a new PET/CT imaging method that uses a special dye to spot kidney scarring (fibrosis) in people with chronic kidney disease. The goal is to see if this scan can accurately measure fibrosis without needing a needle biopsy. 150 patients will be scanned, and the re…

This study tests whether combining different doses of esketamine and dexmedetomidine can improve pain relief after scoliosis correction surgery. About 312 adults will receive one of several drug combinations alongside standard painkillers. The goal is to reduce pain and the need …

This study tests whether a program called the Model of Occupational Harmony (MOHar) can help people with sleep disorders sleep better and feel better. Forty adults with poor sleep will either get this program—which helps them redesign their daily routines with an occupational the…

This study looks back at data from nearly 49,000 births to see if epidural or spinal pain relief during labor is linked to infections in mothers or newborns. Researchers will compare women who had this type of pain relief with those who didn't, checking for fevers, chorioamnionit…

This study examines 15 proteins on prostate cancer cells from 1,600 patients to see which ones are common and whether they relate to survival. Researchers will analyze stored tissue samples and collect new ones from men with advanced cancer. The goal is to understand these protei…

This study aimed to compare two ways of managing pain during abdominal surgery in people aged 50-70 with isolated systolic hypertension. One method uses opioids, the other uses an epidural. The goal was to see which leads to shorter hospital stays and fewer complications. However…

This study follows 150 patients with functional adrenal tumors to see how their heart and blood pressure change before and after surgery. Researchers will use heart ultrasounds and blood pressure monitoring to understand recovery and risks. The goal is to help doctors choose bett…