New combo aims to ease Post-Surgery pain without strong opioids

NCT ID NCT06062550

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining different doses of esketamine and dexmedetomidine can improve pain relief after scoliosis correction surgery. About 312 adults will receive one of several drug combinations alongside standard painkillers. The goal is to reduce pain and the need for strong opioids, which can cause side effects and tolerance.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing University First Hospital

    Beijing, Beijing Municipality, 100034, China

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