Medical University Of Vienna

This study is observing patients who have a major type of heart attack (STEMI) to see how they do after being treated with a special drug-coated balloon instead of the standard metal stent. The goal is to collect real-world data on whether this balloon procedure is safe and works…

This study is testing a new drug called BT200 for adults with type 2B von Willebrand disease, a rare inherited bleeding disorder. Participants will give themselves a weekly injection of either the drug or a placebo for four weeks, then switch after a break. The main goal is to se…

This study is testing whether a drug called datopotamab-deruxtecan can shrink breast cancer tumors that have spread to the brain. It's for people with a hard-to-treat type called triple-negative breast cancer who have new or growing brain metastases. The main goal is to see how w…

This study is testing a new approach for children and young adults whose brain tumors have come back or gotten worse. It uses a combination of several drugs given continuously at low doses, aiming to control the tumor's blood supply with fewer side effects. The main goal is to se…

This study compares two different medical devices used to repair dangerous aortic aneurysms. Researchers will measure how long each device takes to implant and how well the repaired blood vessels hold up over time. The trial involves 126 patients with complex aortic aneurysms who…

This study is testing a special lens implant designed to correct high astigmatism, which causes blurry vision. It's for people who have already had both a corneal transplant and cataract surgery but still have significant vision problems. Researchers will implant the lens and tra…

This study is testing if a second, quick balloon inflation during a minimally invasive heart valve replacement (TAVI) makes the new valve work better and last longer. Patients with severe aortic valve narrowing will be randomly assigned to receive either the standard procedure or…

This study is observing how well an already-approved eye drop (Vevizye®) works for people with moderate to severe dry eye disease who still have inflammation and symptoms after using artificial tears. It will measure changes in eye dryness, redness, and other signs over 12 weeks.…

This study aims to check how well different medical devices measure a patient's blood flow and fluid needs while they are on a special life support machine called ECMO. Researchers will test 30 adult patients in intensive care who are on ECMO for severe lung failure. They will co…

This study is testing if a 6-week outpatient pulmonary rehabilitation program can help people who are still having symptoms after a pulmonary embolism (a blood clot in the lungs). It will compare an immediate rehab group to a waitlist group to see if rehab improves how far patien…

This study is testing whether taking a specific probiotic supplement daily can reduce the symptoms of overactive bladder, a common condition causing frequent and urgent urination. Researchers will compare the probiotic against a placebo pill in 100 women over six months. The main…

This study is testing whether a non-invasive brain stimulation treatment can help people with Long COVID who experience persistent fatigue, brain fog, and mood changes. Researchers will compare the real treatment to a placebo in 102 participants to see if it reduces their fatigue…

This study is comparing several newer types of artificial lenses used in cataract surgery. It aims to see which lenses provide the best vision for tasks like seeing at intermediate distances (like a computer screen), reading, and seeing in low contrast. The study involves about 4…

This study is testing whether listening to music during the start and end of anesthesia can help reduce anxiety and improve comfort for adults having eye surgery. 100 patients will be randomly assigned to either listen to their own music or have no music, and researchers will com…

This small pilot study is exploring whether a low dose of radiotherapy can safely reduce pain and improve symptoms for people with arthritis in their jaw joint. Researchers will track side effects and pain levels in 10 participants using questionnaires and pain scales. The main g…

This study aims to understand how different types and amounts of early physical therapy (like sitting up or walking) affect recovery for intensive care patients worldwide. Researchers will observe over 6,000 patients across 200+ hospitals to see which therapy approaches lead to b…

This study aims to understand how often doctors can identify treatable causes during out-of-hospital cardiac arrests using bedside tests and checklists. Researchers will observe 100 patients to see if finding these causes changes treatment and affects survival. The study also mea…

This study investigates whether performing CPR chest compressions affects how well medical professionals remember patient history information. Researchers compare memory recall when participants perform CPR versus when they simply listen to patient details. The goal is to underst…

This study aims to understand if a specific blood test (anti-factor Xa activity) can predict the risk of dangerous blood clots in critically ill patients in the intensive care unit. Researchers will observe 1,300 patients to see how the test results relate to clot formation, blee…

This study aims to find out if simple blood tests taken right after surgery can predict which older patients will develop sudden confusion, known as delirium. Researchers will observe 1,170 patients aged 65+ having major surgery, checking their blood for specific markers and asse…

This study aims to understand if improvements in how far patients with thickened heart muscle can walk relate to better blood flow in their heart. Researchers will follow 20 patients already receiving standard medications for one year, using heart scans and walking tests. The goa…

This study aims to understand the long-term effects of gender-affirming hormone therapy (GAHT) on heart health, body fat distribution, metabolism, and psychological well-being. Researchers will follow 60 transgender men and women for up to 10 years, using MRI scans, blood tests, …

This study aims to understand how the healthy eye's use of oxygen changes as people get older. Researchers will measure eye oxygen levels in 50 healthy adults aged 18 to 80 using special eye scans. The goal is to create a normal reference for future studies on eye diseases linked…

This study is testing whether using video translators on tablets is practical for ambulance doctors treating patients who speak different languages. It will involve 50 awake adult patients who speak languages like Arabic, Turkish, or Farsi. Researchers will check if the technolog…

This study aims to find out which of two common medical tools is better for safely placing a breathing tube through the nose of babies under 1 year old who have heart defects and need surgery. It will compare a standard direct-view tool against a newer video-guided tool. The main…

This study aims to check if common hospital devices that monitor heart function and blood flow give accurate readings for patients on a life support machine called VA ECMO. Researchers will test 30 adult patients on this machine by comparing measurements from different devices du…

This study aims to understand how gender-affirming hormone therapy affects heart and liver health. Researchers will use MRI scans and blood tests to measure changes in heart function, organ fat, and diabetes risk in 40 transgender adults over 6 months of treatment. The goal is to…

This study aims to precisely measure how a custom-made device used to widen the upper jaw changes both the underlying bone and the overlying soft tissues, like the nose. Researchers will track these changes in 38 adolescents and young adults (ages 12-26) who need this treatment f…

This study aims to understand the long-term health problems that can affect people after a serious stay in the Intensive Care Unit (ICU), known as Post-Intensive Care Syndrome (PICS). It will follow 5,000 adult ICU survivors and their families for up to five years, collecting hea…

This study aims to better understand advanced liver cirrhosis by closely observing 10,000 patients over time. It collects detailed health information and optional biological samples to learn how the disease progresses and what affects patient survival. The goal is to gather knowl…

This study aims to understand why electroconvulsive therapy (ECT) works for some people with severe depression but not others. Researchers will scan the brains and test blood and spinal fluid of 30 patients before and after ECT treatment to look for patterns. The goal is to find …