Medical University Of Vienna

This study is testing whether a drug-coated balloon can be used instead of a permanent stent during emergency heart attack treatment. The balloon delivers medication to open the blocked artery and may reduce complications like blood clots or improper stent placement. Researchers …

This study looks at whether giving an extra balloon inflation after placing a new heart valve (TAVI) helps the valve open more evenly and work better. About 146 people with severe aortic stenosis will be randomly assigned to receive this extra step or not. The goal is to see if i…

This study compares two types of stents used to repair bulges in the main artery (aortic aneurysms). About 126 adults will be randomly assigned to receive either the BeFlared or the VBX stent during a minimally invasive procedure. The goal is to see which device takes less time t…

This study tests a new way to prevent permanent low parathyroid hormone after thyroid surgery. Surgeons will inject mashed parathyroid tissue into the forearm muscle of 100 adults during their thyroid operation. The goal is to see if this simple injection can produce enough hormo…

This study tests a drug called datopotamab-deruxtecan in 20 people with triple-negative breast cancer that has spread to the brain. The goal is to see if the drug can shrink brain tumors. Participants must have new or growing brain metastases and have not had certain prior treatm…

This study tests a combination of low-dose chemotherapy and targeted drugs to control recurrent brain tumors in children. The goal is to extend survival while maintaining a good quality of life. About 232 children with medulloblastoma, ependymoma, ATRT, or other rare CNS tumors w…

This study tests a new drug called BT200 in 4-6 adults with type 2B von Willebrand disease who have low platelets and a history of bleeding. The drug is designed to slow the breakdown of a key clotting protein, which may raise platelet levels and reduce bleeding. Participants wil…

This study checks how accurate standard circulation monitors are for patients on ECMO, a machine that pumps and oxygenates blood outside the body. Researchers will compare three different monitoring methods in 30 adults aged 18–75 who are on ECMO. The goal is to improve how docto…

This study checks if standard heart and blood flow monitors work correctly in patients on ECMO, a machine that adds oxygen to blood outside the body. Researchers will compare three monitoring methods in 30 adults on ECMO for severe lung failure. The goal is to improve how doctors…

This study tests whether a small device that gently stimulates a nerve in the ear can help people with long-term back pain when used along with standard rehab. About 48 adults with chronic back pain will either get the ear stimulation plus rehab or rehab alone for 3 weeks. The go…

This study tests if a 6-week outpatient pulmonary rehabilitation program can improve breathing and walking ability in people with post-PE syndrome, a condition where symptoms like shortness of breath persist after a pulmonary embolism. About 48 adults will be randomly assigned to…

This study looks at whether playing a patient's favorite music during the start and end of anesthesia can lower anxiety and improve comfort. About 100 adults having eye surgery will be randomly assigned to either hear music or not. Researchers will measure anxiety levels and ask …

This study tests a special add-on lens to correct high astigmatism (blurry vision) in people who have had a cornea transplant and cataract surgery. About 40 participants will receive the lens and be followed for up to 7 months to see if their vision improves. The goal is to reduc…

This pilot study tests whether a low dose of radiation to the jaw joint can safely reduce pain from arthritis. Ten adults aged 50 and older with jaw joint arthritis will receive the treatment and report their pain levels and any side effects. The goal is to see if this approach i…

This study tests whether taking a daily lactobacillus probiotic can reduce symptoms of overactive bladder in women. One hundred women with the condition will take either the probiotic or a placebo for six months. Researchers will track symptom changes and check the bacteria in th…

This study compares several types of approved artificial lenses (intraocular lenses) used in cataract surgery to see which one provides the clearest vision at intermediate distances, like reading a computer screen. About 461 people with age-related cataracts will receive a differ…

This study tests a new treatment called transcranial pulse stimulation (TPS) for people with Post-COVID syndrome who suffer from fatigue, memory problems, or mood changes. TPS uses gentle sound waves to stimulate the brain. Half of the 102 participants will get real TPS, and the …

This early-stage study explores whether psilocybin, the active ingredient in magic mushrooms, can reduce anhedonia (loss of pleasure) in people with major depression. 85 participants, including healthy volunteers, will receive psilocybin in two sessions—one with a drug that block…

This study looks at whether a new cyclosporin eye drop (Vevizye®) can reduce inflammation and dryness in people with moderate to severe dry eye disease who still have symptoms after using artificial tears. About 25 adults with chronic dry eye and visible eye redness will use the …

This study looks at how widening the upper jaw changes both the bones and the soft tissues of the face. About 38 people with a narrow upper jaw and crossbite will receive a custom-made expander anchored to temporary bone pins. Researchers will use 3D scans to measure the exact ch…

This study looks at whether performing chest compressions makes it harder for medical workers to recall a patient's medical history. Thirty-eight trained professionals will do CPR while listening to a patient story, then answer questions. The goal is to understand how multitaskin…

This study looks at whether special brain monitors can give early clues about recovery in people who need emergency life support after a heart stoppage. Researchers will test two devices—a pupil scanner and a brain oxygen sensor—on 45 adults before and after starting ECMO. The go…

This study looks at whether using a video laryngoscope helps doctors place a breathing tube through the nose more successfully on the first try compared to a standard direct laryngoscope. It involves 180 infants under 1 year old with congenital heart disease who are scheduled for…

This study follows 10,000 adults with advanced chronic liver disease to see how their health changes over time. Researchers will collect medical data and samples like blood, urine, and tissue to better understand cirrhosis and its complications. Participants receive regular check…

This study tests a new drug that blocks a specific nerve channel (NaV1.8) to see which types of pain it reduces. Healthy volunteers receive tiny, safe doses injected into the skin and undergo brief pain tests like heat, cold, and pressure. The goal is to understand pain better an…

This study follows 5,000 adults who spent more than 72 hours in the ICU to understand long-term problems with thinking, physical health, and emotions. Researchers will collect data during the hospital stay and for up to five years after discharge. The goal is to find risk factors…

This study looks at how gender-affirming hormone therapy changes heart function, fat levels in the heart and liver, and insulin sensitivity. Researchers will follow 40 transgender adults (20 male-to-female, 20 female-to-male) for 6 months using MRI scans and glucose tests. The go…

This study tests whether using a tablet for video interpreting helps emergency doctors talk with patients who don't speak the same language. 50 awake adults with language barriers will take part. Researchers will check if the technology works, how easy it is to use, and whether i…

This study follows transgender men and women who have been on gender-affirming hormone therapy for 2 years to see how it affects their heart, liver, pancreas, and insulin system over 2, 5, and 10 years. Participants will have MRI scans, blood tests, and psychological surveys. The…

This study looks at how certain diabetes medications (semaglutide, liraglutide, tirzepatide) change blood flow and oxygen use in the eyes of people with diabetes. About 20 adults with diabetes will have their eye blood flow and oxygen levels measured before and after starting one…

This study looks at how the retina's ability to use oxygen changes as people age. Researchers will measure oxygen extraction in healthy adults aged 18 to 80 using non-invasive eye scans. Participants will also breathe pure oxygen to see short-term effects. The goal is to understa…

This study looks at people with a thickened heart muscle condition (hypertrophic obstructive cardiomyopathy) who are already on the best available medications. Researchers want to see if changes in blood flow to the heart over one year are linked to how far a person can walk in s…

This study is for people newly diagnosed with a type of aggressive brain cancer called glioblastoma. Researchers will take a sample of the tumor during surgery and grow the cells in a lab to test which drugs kill them best. Based on those results, participants may receive a perso…

This study is for adults aged 65 and older having major surgery. Researchers want to see if certain substances in the blood, measured right after surgery, can predict whether a patient will experience postoperative delirium—a state of sudden confusion. The goal is to find a relia…

This study aims to understand how different types of early movement and rehabilitation in the intensive care unit (ICU) affect patients' recovery. Researchers will observe over 6,000 adults from ICUs around the world, recording their usual care and tracking their physical functio…

This study looks at how electroconvulsive therapy (ECT) changes the brain in people with severe depression. Researchers will use MRI scans and lab tests before and after ECT to find clues that predict who will get better. The goal is to make ECT more personalized and effective fo…

This study observes 1,300 critically ill ICU patients to see if the level of a blood thinner (enoxaparin) in their blood is linked to dangerous blood clots. Researchers will track clots, bleeding, and patient outcomes like survival and hospital stay length. The goal is to find be…