Could lying on the stomach help infants breathe easier?
NCT ID NCT05002478
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial investigates whether placing infants with severe acute respiratory distress syndrome (ARDS) on their stomachs (prone positioning) after surfactant treatment can improve their oxygen levels. The study involves 14 mechanically ventilated infants, comparing oxygenation and lung imaging measurements in prone versus supine positions. The goal is to see if this simple positioning change could be a beneficial supportive therapy for these critically ill infants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Prone positioning (turning the infant onto their stomach) after surfactant administration
- What this could lead to
- If prone positioning improves oxygenation in these infants, it could become a standard supportive care strategy for severe ARDS in this age group.
- What could go wrong
- This is a very small, early-stage trial (14 infants), so results may not apply broadly. Prone positioning has potential risks, such as pressure sores or accidental tube displacement, and may not improve outcomes for all infants.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Medical University of Vienna
RECRUITINGVienna, 1090, Austria
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