Mcgill University Health Centre/research Institute Of The Mcgill University Health Centre

This study tested whether a structured program combining exercise, nutritional advice, and psychological support is safe and doable for frail adults with cirrhosis waiting for a liver transplant. Twenty-five participants were enrolled to see if they could stick with the program a…

This study tested whether taking a higher dose of the drug rifampin for 2 months is as safe and effective as the standard 4-month dose for treating latent tuberculosis (TB) infection. Over 1,300 adults and children aged 10 and older with latent TB were randomly assigned to receiv…

This study looked at 201 Canadian patients with ANCA-associated vasculitis to see if cheaper biosimilar versions of rituximab work as well as the original drug. Researchers compared disease control, side effects, and how long it took to get insurance approval for treatment. The g…

This study compares a newer weight-loss surgery called SADI-S to an older, more complex one called BPD-DS in 62 adults with severe obesity. The goal is to see if SADI-S is safer and just as effective for long-term weight loss and managing related health problems like diabetes. Re…

This study tested whether giving recombinant human growth hormone for 48 weeks could reduce the hidden HIV reservoir in people already on successful antiretroviral therapy (ART). The goal was to move toward a 'functional cure' where the body can control the virus without lifelong…

This study tested whether a special smartwatch (Watch HOP) can help detect heart failure by measuring heart rate, movement, skin temperature, and voice patterns. Researchers compared 56 people with and without heart failure during physical tasks and daily life. The goal is to fin…

This pilot study tested a virtual program designed to help older men at high risk for fractures reduce their risk of falls and broken bones. The program included personalized exercise plans delivered through a smartphone app and virtual nutrition counseling. Researchers enrolled …

This study tested whether extending standard vancomycin treatment for C. diff infection with a 2-week taper (lowering the dose gradually) reduces the chance of the infection returning. 263 adults who had a first episode or first recurrence of C. diff were randomly assigned to rec…

This study tested whether adding empagliflozin (a diabetes drug) to standard diuretics helps hospitalized heart failure patients with moderate to advanced kidney disease urinate more fluid. 25 participants were given the combination, and researchers measured urine output. The goa…

This study tested an online, self-guided program called eParenting CARE for parents of children aged 8-13. The program teaches emotion regulation and supportive parenting strategies over five weeks. Researchers enrolled 67 parents in Canada to see if the program is feasible and a…

This study tested a coaching program for families of young children (ages 1.5 to 4.5 years) with suspected or confirmed developmental delays. The program included regular coaching sessions, online education, and peer support over 18 months. Researchers measured whether this appro…

This study tested whether giving a drug called dobutamine during major non-cardiac surgery and using a special ultrasound (speckle tracking) can identify patients at higher risk of heart attack or death after surgery. The researchers enrolled 140 adults undergoing major abdominal…

This study compared two procedures for getting a liver biopsy and measuring liver pressure in people with chronic liver disease or cirrhosis. One method uses a scope through the mouth (endoscopic ultrasound), the other goes through a vein in the neck (transjugular). The goal was …

This study looked at 37 people with COPD who were having a lung-attack (sudden worsening of breathing). Researchers compared two treatment strategies: using only short-acting rescue inhalers versus adding long-acting inhalers. They used a safe, easy breathing test called oscillom…

This completed study tested whether a smartwatch, combined with artificial intelligence, could identify digital signs of type 2 diabetes. Researchers gave 210 adults a multisensor watch to track heart rate and other vitals, then analyzed the data with machine learning. The goal w…

This study tested a mobile app designed to educate parents and caregivers of children with epilepsy. The app provides information about the condition, tracks symptoms, and helps manage appointments. Researchers wanted to see if using the app for one month would increase parents' …