Mcgill University Health Centre/research Institute Of The Mcgill University Health Centre

This study tested whether taking a higher dose of the antibiotic rifampin for 2 months is as safe and effective as the standard 4-month treatment for latent tuberculosis (TB). About 1,368 adults and children aged 10 and older with latent TB took part. Participants received either…

This study looked at 201 Canadian patients with ANCA-associated vasculitis to see if a cheaper biosimilar version of rituximab works as well as the original drug. Researchers compared how well the drugs controlled the disease, side effects, and how long patients waited for approv…

This pilot study tested whether a telehealth program combining strength training, balance exercises, and nutrition advice could help older men at high risk for falls and fractures. Forty-five men aged 60 and older participated. The goal was to see if the program was practical and…

This study tested a newer, simpler weight loss surgery called SADI-S against a standard, more complex one (BPD-DS) in 62 adults with severe obesity. The goal was to see if SADI-S is safer and works as well for weight loss and related health problems like diabetes. Researchers mea…

This study tested whether a smartwatch can detect heart failure by tracking body signals like heart rate and movement, and recording voice patterns. Researchers compared 56 people with and without heart failure during physical tasks and daily life. The goal is to find patterns th…

This study looked at whether giving a gradual, lower dose of vancomycin for two extra weeks after the standard treatment can prevent C. diff infection from coming back. About 263 adults who had their first or second C. diff infection took part. Half received a placebo and half re…

This study looked at whether adding empagliflozin (a diabetes drug) to standard water pills helps people with acute heart failure and moderate-to-severe kidney disease urinate out more excess fluid. 25 adults participated, and researchers measured urine output after combining the…

This study looked at which combination of inhalers works best to open the lungs during a sudden worsening of COPD (called a lung attack). 37 people with COPD who were being treated for a lung attack took part. They used a gentle breathing test called oscillometry to measure lung …

This study tested a coaching program for 306 parents of children aged 1.5 to 4.5 years with suspected or confirmed developmental delays. The program included a personal coach, online tools, and a peer support network. Researchers measured whether this approach improved parents' s…

This study tested whether a structured program of exercise, nutritional advice, and psychological support is safe and practical for frail patients with cirrhosis waiting for a liver transplant. 25 adults on the transplant list took part. The goal was to see if patients could stic…

This study tested whether giving recombinant human growth hormone for 48 weeks could reduce the hidden HIV reservoir in people already on successful antiretroviral therapy (ART). 22 adults with undetectable viral loads and healthy immune systems took part. The goal was to see if …

This study tested a mobile app designed to educate parents and caregivers of children with epilepsy. The goal was to see if using the app for one month could improve parents' knowledge about epilepsy and reduce their anxiety about seizures. The study involved 72 caregivers of chi…

This study tested whether an online, self-guided program called eParenting CARE is practical and helpful for parents of children aged 8 to 13. The program teaches parents skills to manage their own emotions and support their child's emotional well-being. Researchers enrolled 67 p…

This study tested whether a smartwatch could help identify digital signs of type 2 diabetes. Researchers gave 210 adults a special watch to track health data like activity and heart signals. They used artificial intelligence to find patterns linked to diabetes. The goal was to im…

This study compared two methods for taking a liver biopsy and measuring blood pressure in the liver: the newer endoscopic ultrasound (EUS) approach versus the standard transjugular (TJ) method. 58 adults with chronic liver disease or portal hypertension took part. The goal was to…