New scope method challenges standard liver biopsy

NCT ID NCT05118308

Completed Knowledge-focused Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two procedures for getting a liver biopsy and measuring liver pressure in people with chronic liver disease or cirrhosis. One method uses a scope through the mouth (endoscopic ultrasound), the other goes through a vein in the neck (transjugular). The goal was to see which approach works better and is safer. 58 adults took part, and the results will help doctors choose the best technique.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that endoscopic ultrasound is a safer or more effective way to get liver tissue and measure liver pressure, potentially changing standard practice.
What could go wrong: This is a small, completed trial with only 58 participants. Results may not apply to all patients, and the new method might not be better or could have unforeseen risks.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis liver disorder portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC LIVER DISEASE CIRRHOSIS PORTAL HYPERTENSION

Contacts and locations

Locations

McGill University Health Centre

Montreal, Quebec, H3G1A4, Canada

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