Mcgill University Health Centre/research Institute Of The Mcgill University Health Centre

This study compares three catheter ablation techniques for people with persistent atrial fibrillation (AFib), a heart rhythm problem lasting 3 months to 3 years. About 617 adults having their first ablation will be randomly assigned to one of three strategies. The goal is to see …

This study gives one child with Cree leukoencephalopathy (CLE) access to an experimental drug called fosigotifator. CLE is a rare, inherited brain disease that destroys white matter and leads to early death. The drug targets the genetic cause of the disease and may slow or stop b…

This study provides an experimental drug called fosigotifator to one patient with Cree Leukoencephalopathy, a rare and deadly brain disease that currently has no treatments. The goal is to see if the drug can slow or stop the brain damage and improve quality of life. The patient …

This study tests a new catheter that uses a combination of pulsed field and radiofrequency energy to destroy the small areas of heart tissue causing ventricular tachycardia (a fast, dangerous heart rhythm). About 30 adults with recurrent VT will receive this ablation procedure. T…

This study looks at whether canagliflozin, a drug used for diabetes, can safely reduce kidney damage in people with advanced chronic kidney disease (CKD), including those on dialysis. About 35 adults with stage 4 or 5 CKD will take the drug for up to 26 weeks. Researchers will me…

This study tests a new wireless sensor that continuously measures the amount of light therapy a newborn receives for jaundice. Currently, doctors check light levels only once a day with a handheld device, which may not be accurate. The goal is to see if the new sensor provides be…

This study is testing whether wireless sensors can safely and accurately monitor heart rate, breathing, temperature, and oxygen levels in 75 newborn babies in the NICU. The goal is to see if these sensors work as well as the standard wired monitors, and to gather feedback from do…

This study explores whether a new, non-invasive acoustic sensor can reliably detect breathing sounds and problems in premature infants. Researchers will monitor 50 preterm babies in the NICU, comparing the sensor's readings to standard airflow measurements. The goal is to see if …