Which ablation strategy works best for stubborn AFib?
NCT ID NCT04428944
First seen May 12, 2026 · Last updated May 12, 2026
Summary
This study compares three catheter ablation techniques for people with persistent atrial fibrillation (AFib), a heart rhythm problem lasting 3 months to 3 years. About 617 adults having their first ablation will be randomly assigned to one of three strategies. The goal is to see which method best prevents AFib from returning for at least 18 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AZ Sint-Jan
Ruddershove, Belgium
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Alfred Health
Melbourne, Australia
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Antwerp University Hospital (UZA)
Edegem, Belgium
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Brigham & Women'S Hosptial Inc.
Boston, Massachusetts, 02115, United States
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Canberra Heart Rhythm Foundation
Garran, Australian Capital Territory, Australia
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Clinique du Tonkin
Villeurbanne, France
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Dokkyo Medical University Koshigaya Hospital
Koshigaya, Saitama, Japan
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Hamilton General Hospital
Hamilton, Ontario, L8L 2X2, Canada
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Hospital Clinic Barcelona
Barcelona, Spain
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Hospital St-Joseph
Marseille, France
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Hôpital Fleurimont, CHUS
Sherbrooke, Quebec, J1H 5H3, Canada
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Institut Mutualiste Montsouris
Paris, 75014, France
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Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ)
Québec, Quebec, G1V 4G5, Canada
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Jikei University School of Med
Tokyo, Japan
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Juntendo University Hospital
Bunkyo City, Tokyo, Japan
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Laurent Macle
Montreal, QC - Québec, H1T 1c8, Canada
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MUHC, McGill University Health Centre
Montreal, Quebec, H4A 3J1, Canada
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Medical University of Graz
Graz, Austria
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Minamino Cardiovascular Hospital
Tokyo, Japan
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National University Corporation Kobe University
Chūōku, Japan
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Nihon University School of Medicine
Tokyo, Japan
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OLV Hospital Aalst
Aalst, Belgium
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Ordensklinikum Linz GmbH
Linz, Austria
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Ospedale Generale Regionale F. Miulli
Acquaviva delle Fonti, Italy
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Royal Adelaide Hospital and Cardiovascular Centre
Adelaide, Australia
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Royal Jubilee Hospital
Victoria, British Colombia, V8R 1J8, Canada
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Royal Melbourne Hospital
Parkville, Australia
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Southlake Regional Health Center
Newmarket, Ontario, L3Y 2P9, Canada
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St. Paul's Hospital, Vancouver, BC
Vancouver, British Colombia, V6Z 1Y6, Canada
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University of Calgary Foothills
Calgary, Alberta, T2N 4N1, Canada
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University of Ottawa Heart Institute
Ottawa, Quebec, K1Y 4W7, Canada
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Vancouver General Hospital
Vancouver, British Colombia, V5Z 1M9, Canada
Conditions
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