Kocaeli University

This study tested whether an antioxidant supplement called Proxeed Plus could improve sperm motility in men with asthenozoospermia (low sperm movement), a common cause of male infertility. Thirty men took either the supplement or a placebo daily for three months. Researchers meas…

This trial investigates whether a 20-minute warm-water footbath containing magnesium sulfate can reduce pain in women with primary dysmenorrhea (painful periods). Around 120 women aged 18–35 are randomly assigned to receive the magnesium footbath, a plain warm-water footbath, or …

This study tests two non-drug approaches to help children aged 7–12 feel less pain, fear, and anxiety during a blood draw. One group uses Buzzy®, a device that applies cold and vibration near the needle site. Another group receives a cognitive behavioral package that includes age…

This study tested three non-drug methods to reduce pain, fear, and anxiety during subcutaneous injections in 45 children aged 6–12 with cancer. The approaches were Buzzy® (a device that vibrates and cools the skin), a cognitive-behavioral coaching package, and a kaleidoscope for …

This study tested whether a 30-minute warm foot bath after a colonoscopy can help reduce pain and bloating and help people pass gas sooner. 90 adults were randomly assigned to either get the foot bath or standard care. Researchers measured pain and bloating right after the proced…

This study tested whether injecting lidocaine, a numbing medicine, at two different strengths (0.5% vs 1%) could reduce pain from the head holder used during brain surgery. 75 patients were split into two groups and received the injection before surgery. Researchers then compared…

This study looked at two treatments for jaw pain caused by teeth grinding (bruxism) and related muscle pain. Forty adults either got a custom mouth splint to wear most of the day or had thin needles inserted into their jaw muscles (dry needling) in three weekly sessions. Research…

This study compared two ways to fix a tight upper lip frenulum (lip-tie): using a scalpel or a diode laser. Some patients also got low-level laser therapy after surgery to help healing. The trial measured pain, speech, chewing, and quality of life in 94 adults. Results may help d…

This completed trial tested whether reflexology (a type of foot massage) can reduce pain during episiotomy repair after vaginal birth. 80 women were randomly assigned to receive either reflexology plus standard local anesthesia or standard care alone. Pain was measured using a vi…

This study tested whether a soft rehabilitation glove could improve hand movement and daily activities in people who had a stroke more than three months ago. Thirty-four participants used the glove for 20 minutes a day, five days a week, for three weeks, alongside standard therap…

This study tested whether using virtual reality (VR) for relaxation helps mothers of premature babies produce more breast milk and feel more confident about breastfeeding. Forty-four first-time mothers with babies in the NICU used a VR headset showing calming nature scenes and mu…

This study looked at whether doing a mandala coloring activity could lower stress and fear of childbirth in women hospitalized with high-risk pregnancies. 149 pregnant women took part. The researchers measured their anxiety, stress, and fear levels before and after the activity.

This study tested two simple distraction methods—blowing bubbles and a mental game with praise—to help children aged 7 to 12 feel less pain, fear, and anxiety during a blood draw. 207 children took part, and their pain and fear levels were measured before and after the procedure.…

This study looked at whether back massage after open heart surgery can help with pain, sleep, and stress. 96 adults who had elective open heart surgery were included. The massage group received three 30-minute back massages on the first day after surgery. Researchers measured pai…

This study tested a play-based program called TOTEM for 4-6 year old children who survived the earthquake in Kahramanmaraş, Turkey. 53 children took part in 8 play sessions over 5 weeks. Researchers measured their anxiety, sleep, and overall emotional well-being before and after …

This study tested whether listening to calming music during urodynamic testing—an invasive procedure for bladder problems—can reduce pain and embarrassment. 90 adults were randomly assigned to listen to classical music or not during the test. Researchers measured pain and embarra…

This study tested whether applying a cold spray to the skin right before a low molecular weight heparin injection can reduce pain and bruising in patients recovering from orthopedic surgery. Researchers measured pain using a simple scale and bruise size with a clear grid. The goa…

This study compared two types of nerve blocks—erector spinae plane (ESP) and rhomboid intercostal (RIB)—for managing pain after breast surgery. 84 patients received one of the blocks before their operation. Researchers measured how much morphine they needed afterward and their pa…

This study looked at whether listening to calming instrumental music before a coronary angiography (a procedure to check heart arteries) can help patients feel less pain and anxiety, and improve their comfort and satisfaction. Researchers divided 210 patients into two groups: one…

This study tested whether giving mothers a mirror to watch their baby's birth during the pushing stage could shorten labor and improve their experience. 122 healthy women in Turkey were split into two groups: one used a mirror, the other had standard care. After birth, mothers fi…

This study tested whether playing virtual reality games can help people with frozen shoulder (adhesive capsulitis) feel less pain, move their shoulder better, and improve their quality of life. Thirty-six adults with the condition used VR exercises as part of their treatment. Res…

This study investigates the effects of membrane stripping—a procedure where the membranes around the baby are gently swept during a vaginal exam—on first-time mothers giving birth at term. Researchers will measure pain during exams, cervical readiness, postpartum bleeding, and bi…

This study looked at two ways of teaching new mothers how to comfort their babies during heel prick blood tests. One group got verbal instructions plus a brochure, the other got verbal instructions plus an AI-supported video. Researchers measured mothers' anxiety, how well they u…

This study looked at 99 heterosexual men with HIV who are on effective antiretroviral therapy and have undetectable virus levels, comparing them to healthy men without HIV. Participants filled out questionnaires about their quality of life, depression symptoms, and sexual functio…

This study tested whether wearing stroboscopic glasses during practice could improve cognitive skills in 34 adolescent male volleyball players. For eight weeks, the players wore the glasses for 10 minutes a day, two days a week, while training. Researchers measured changes in vis…

This study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect increased brain pressure during laparoscopic (keyhole) surgery. Researchers measured the nerve sheath diameter in 55 adults undergoing laparoscopic surgery.…

This study looked at 197 ICU patients with bloodstream infections caused by carbapenem-resistant bacteria (superbugs). Researchers used machine learning to analyze patient data and predict which patients were at higher risk of dying. The goal is to create a tool that helps doctor…

This completed study looked at whether a new monitoring tool called Oxygen Reserve Index (ORi) can give earlier warning of low oxygen levels in patients having varicose vein surgery under spinal anesthesia. The study included 56 adults and compared standard oxygen monitoring with…

This completed study tested two ways of helping patients breathe during microscopic throat surgery. One method uses a steady airflow, while the other uses a set volume of air. The goal was to see which method keeps airway pressure lower and safer. 68 adults having elective laser …

This study tested a 10-week group education program for parents of autistic preschoolers in Türkiye. The program taught naturalistic teaching strategies to help parents support their child's development. Researchers measured changes in parents' confidence and tracked how many fam…

This study looked at saliva from 21 people: some with oral lichen planus, some with oral leukoplakia, and some healthy. The goal was to see if proteins in saliva are different between these groups. Researchers hope these protein differences could one day help doctors tell these t…