Walking vs. cycling: which sparks your Cells' Self-Cleanup?
NCT ID NCT07536659
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a single session of walking or cycling changes certain proteins in the blood that are linked to autophagy—the body's way of cleaning out damaged cells. Forty healthy men aged 18-35 will walk or cycle, and researchers will measure three autophagy-related proteins before and after exercise. The goal is to learn more about how different types of exercise affect cell health without needing invasive muscle biopsies.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 20 healthy male volunteers aged between 18 and 35 years, who engage in physical activity at least 2-3 days per week for a minimum of 30 minutes and have no known health problems, will be included in the study. To avoid the effects of previous medical conditions, individuals with acute or chronic injuries in the bilateral/unilateral lower extremities, musculoskeletal disorders, or a history of surgical intervention to the hip and/or knee joints will be excluded from the study. Participants will be instructed to minimize all sports activities 48 hours prior to the assessment days; however, normal daily activities such as walking and stair climbing will be permitted. In addition, participants will be advised to maintain their usual daily routines and to consume the same types of food on the assessment days.
- Ages
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18 to 35 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy male volunteers aged 18-35 * Engaging in physical activity at least 2-3 days per week for a minimum of 30 minutes * Having no known health problems Exclusion Criteria: * Individuals with acute or chronic injuries in the bilateral/unilateral lower extremities * Individuals with musculoskeletal disorders in the bilateral/unilateral lower extremities * Individuals who have undergone surgical intervention to the hip and/or knee joint * Individuals with cardiopulmonary problems that would prevent them from performing exercise
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kocaeli University Faculty of Medicine Hospital
Kocaeli, Turkey (Türkiye)
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Sakarya University of Applied Sciences Physiotherapy and Rehabilitation Research Center
Sakarya, Turkey (Türkiye)