Can a quick cold spray before your shot reduce pain and bruising?

NCT ID NCT07195955

Completed Symptom relief Sponsor: Kocaeli University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether applying a cold spray to the skin right before a low molecular weight heparin injection can reduce pain and bruising in patients recovering from orthopedic surgery. Researchers measured pain using a simple scale and bruise size with a clear grid. The goal is to find a practical, drug-free way to make daily injections more comfortable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cold spray (topical cooling agent)
What this could lead to: If effective, cold spray could become a simple, low-cost way to reduce pain and bruising from daily blood-thinner injections after surgery.
What could go wrong: This is a small, completed study with no phase designation, so results may not apply broadly. Cold spray might not work for everyone or could cause skin irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Ecchymosis Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLD APPLICATION ECCHYMOSIS NURSING CARE PAIN

Contacts and locations

Locations

Kocaeli University

Köseköy, Kocaeli, 41100, Turkey (Türkiye)

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