Johns Hopkins University
Clinical trials sponsored by Johns Hopkins University, explained in plain language.
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Nepal lung health study: can volunteers clear the air?
Disease control Not yet recruitingThis study tests whether a program led by community health volunteers can improve lung health for people in Bhaktapur, Nepal, who are at risk for chronic lung diseases like asthma or COPD. The program focuses on reducing tobacco smoke and air pollution, preventing infections, and…
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated May 03, 2026 20:04 UTC
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Buddy system for transplant patients: could a peer mentor prevent relapse?
Disease control Not yet recruitingThis study looks at whether having a peer support specialist — someone who has been through a similar experience — can help liver transplant recipients with a history of alcohol-related liver disease stay sober and keep up with their medical care. About 95 participants will be fo…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated May 03, 2026 20:03 UTC
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Can a breathing gadget calm anxious teens?
Symptom relief Not yet recruitingThis study tests a biofeedback breathing system called Freespira in 73 youth aged 9-17 with anxiety or panic disorders. Participants use the device to learn breathing techniques that may reduce symptoms. The goal is to see if this non-drug approach improves anxiety scores on a st…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:08 UTC
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New device could help kids with cancer pain ditch pills
Symptom relief Not yet recruitingThis study tests a non-invasive device called Scrambler Therapy to relieve nerve pain in children with cancer that has spread to the bone. About 70 children will receive the treatment, and researchers will measure changes in pain levels and use of pain medications. The goal is to…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:08 UTC
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Could plugging brain arteries stop migraines? small study aims to find out.
Symptom relief Not yet recruitingThis study tests whether blocking two arteries in the brain (middle meningeal arteries) with a special plug called Onyx can safely reduce chronic migraine pain. About 13 adults with hard-to-treat migraines will get the procedure and be followed for 6 months. The goal is to see if…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:08 UTC
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Can a simple cream prevent wound problems after leg surgery?
Symptom relief Not yet recruitingThis early study tests whether applying a nitropaste cream during high-risk leg surgery can improve blood flow to the wound area, potentially reducing complications like infection or poor healing. About 15 adults having specific ankle, heel, or shinbone surgeries will receive the…
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:03 UTC
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Brain zaps may sharpen minds after head injury
Symptom relief Not yet recruitingThis study tests whether a safe, noninvasive brain stimulation technique called tDCS, combined with thinking exercises, can improve attention and memory in people who had a traumatic brain injury at least two years ago. About 20 adults will receive personalized tDCS while doing c…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:02 UTC
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CBD put to the test: could it ease alcohol withdrawal?
Symptom relief Not yet recruitingThis study looks at whether cannabidiol (CBD) can reduce withdrawal symptoms and cravings in people with moderate-to-severe alcohol use disorder. About 105 adults will stay in a hospital for 5 days, stop drinking, and receive either CBD or a placebo alongside standard care. Resea…
Phase: PHASE2, PHASE3 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:02 UTC
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Robot meditation may boost sleep in seniors with memory worries
Symptom relief Not yet recruitingThis study tests whether a handheld robot that vibrates and talks can help older adults with mild memory problems sleep better. 100 participants will compare robot-guided meditation to standard audio-only meditation. The goal is to see if the robot makes it easier to focus and re…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 03, 2026 20:00 UTC
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Exercise as medicine: could cycling and weights save your sight?
Knowledge-focused Not yet recruitingThis study looks at whether a home-based exercise program (resistance training and stationary cycling) can protect or improve vision in people with glaucoma, a disease that damages the optic nerve. Researchers will measure changes in vision, eye blood flow, and quality of life in…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 03, 2026 20:08 UTC
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Can your eyes reveal if You're too high to drive?
Knowledge-focused Not yet recruitingThis study looks at how different doses of THC (the active part of cannabis) affect eye movements and attention in people who use cannabis often or only occasionally. Researchers want to see if eye-tracking tests can reliably detect impairment from THC. The results could help dev…
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 03, 2026 20:08 UTC
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New study tests if asking parents their goals improves care for preemies with lung disease
Knowledge-focused Not yet recruitingThis pilot study tests whether a pre-visit questionnaire helps Black parents of preterm infants with chronic lung disease set and achieve goals for their child's primary care visits. About 30 parents will fill out the questionnaire before a checkup and then complete follow-up sur…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 03, 2026 20:06 UTC
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Could a common mineral slow Alzheimer's? new study puts lithium orotate to the test.
Knowledge-focused Not yet recruitingThis study tests whether a daily pill of lithium orotate is safe and can reach the brain in people with early Alzheimer's. Forty adults with confirmed Alzheimer's will take either the supplement or a placebo for 9 weeks. Researchers will measure lithium levels in spinal fluid and…
Phase: PHASE1, PHASE2 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 03, 2026 20:04 UTC
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Scientists investigate how cannabis compound and terpene interact in the body
Knowledge-focused Not yet recruitingThis study looks at how THC (the main psychoactive part of cannabis) and beta-myrcene (a natural compound found in many plants) work together when inhaled. Researchers will measure how these substances affect participants' feelings and tiredness. The goal is to better understand …
Phase: PHASE1 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 03, 2026 19:59 UTC